Anti-SON/DBP5 antibody (ab121033)

This fast track antibody is not yet fully characterized. It is subject to these terms and conditions.

Overview

  • Product name

  • Description

    Goat polyclonal to SON/DBP5

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Host species

    Goat
  • Species reactivity


    Predicted to work with: Mouse, Rat, Cow, Dog, Human, a wide range of other species
  • Immunogen

    Synthetic peptide corresponding to Human SON/DBP5 aa 89-101 (N terminal). (NP_115571.1; NP_620305.1)
    Sequence:

    KSRCVSVQTDPTD

  • General notes

     This product was previously labelled as SON

     

Properties

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent concentration. Preliminary experiments gave an approx 35kDa band in Human, Mouse and Rat Heart lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 250kDa according to NP_115571.1. The 35kDa band was successfully blocked by incubation with the immunizing peptide.

Target

  • Function

    Represses hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. Binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3'. Might protect cells from apoptosis. Might be involved in pre-mRNA splicing.
  • Tissue specificity

    Widely expressed, with the higher expression seen in leukocyte and heart.
  • Sequence similarities

    Contains 1 DRBM (double-stranded RNA-binding) domain.
    Contains 1 G-patch domain.
  • Domain

    Contains 8 types of repeats which are distributed in 3 regions.
  • Cellular localization

    Nucleus speckle. Colocalizes with the pre-mRNA splicing factor SFRS2/SC-35.
  • Information by UniProt
  • Database links

  • Alternative names

    • BASS1 antibody
    • Bax antagonist selected in saccharomyces 1 antibody
    • DBP-5 antibody
    • Negative regulatory element-binding protein antibody
    • NRE-binding protein antibody
    • Protein DBP-5 antibody
    • Protein SON antibody
    • SON antibody
    • SON protein antibody
    • SON_HUMAN antibody
    • SON3 antibody
    see all

References

ab121033 has not yet been referenced specifically in any publications.

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