Anti-Sonic Hedgehog antibody [EP1190Y] (ab53281)

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ab53281 has been referenced in 31 publications.

  • Jia J  et al. Fibroblast activation protein-a promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways. Int J Mol Med 41:275-283 (2018). PubMed: 29115573
  • Song X  et al. Activation of hedgehog signaling and its association with cisplatin resistance in ovarian epithelial tumors. Oncol Lett 15:5569-5576 (2018). PubMed: 29552194
  • Tolani B  et al. Preclinical characterization of therapeutic antibodies targeted at the carboxy-terminus of Sonic hedgehog. Oncotarget 9:14311-14323 (2018). PubMed: 29581846
  • Po A  et al. Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma. Oncogene 36:4641-4652 (2017). PubMed: 28368412
  • Gonnissen A  et al. Tissue microarray analysis indicates hedgehog signaling as a potential prognostic factor in intermediate-risk prostate cancer. BMC Cancer 17:634 (2017). PubMed: 28877722
  • Hay JF  et al. Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy. Oncotarget 8:67891-67903 (2017). PubMed: 28978082
  • Wei R  et al. Human CAFs promote lymphangiogenesis in ovarian cancer via the Hh-VEGF-C signaling axis. Oncotarget 8:67315-67328 (2017). PubMed: 28978035
  • Grzelak CA  et al. Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS One 12:e0171480 (2017). IF . PubMed: 28187190
  • Arnold KM  et al. Co-activation of Hedgehog and Wnt signaling pathways is associated with poor outcomes in triple negative breast cancer. Oncol Lett 14:5285-5292 (2017). IHC-P ; Human . PubMed: 29142600
  • Leprieur EG  et al. Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer. Oncotarget 8:103744-103757 (2017). PubMed: 29262597
  • Lin Y  et al. Role of Hedgehog-Gli1 signaling in the enhanced proliferation and differentiation of MG63 cells enabled by hierarchical micro-/nanotextured topography. Int J Nanomedicine 12:3267-3280 (2017). WB ; Human . PubMed: 28458545
  • Hagiwara M  et al. In Vitro Experimental Model for the Long-Term Analysis of Cellular Dynamics During Bronchial Tree Development from Lung Epithelial Cells. Tissue Eng Part C Methods 23:323-332 (2017). IHC-P ; Human . PubMed: 28471293
  • Bhardwaj A  et al. MYB Promotes Desmoplasia in Pancreatic Cancer through Direct Transcriptional Up-regulation and Cooperative Action of Sonic Hedgehog and Adrenomedullin. J Biol Chem 291:16263-70 (2016). WB ; Human . PubMed: 27246849
  • Verrill C  et al. Altered expression of epithelial-to-mesenchymal transition proteins in extraprostatic prostate cancer. Oncotarget 7:1107-19 (2016). PubMed: 26701730
  • Zhang X  et al. Expression of SOX9 and CDX2 in nongoblet columnar-lined esophagus predicts the detection of Barrett's esophagus during follow-up. Mod Pathol 28:654-61 (2015). PubMed: 25412842
  • Li H  et al. Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway. Sci Rep 5:16974 (2015). IHC ; Human . PubMed: 26581960
  • Nakamura M  et al. Metformin suppresses sonic hedgehog expression in pancreatic cancer cells. Anticancer Res 34:1765-9 (2014). Human . PubMed: 24692708
  • Hwang J  et al. The effects of sonic hedgehog signaling pathway components on non-small-cell lung cancer progression and clinical outcome. World J Surg Oncol 12:268 (2014). IHC-P ; Human . PubMed: 25141859
  • Abiria SA  et al. Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling. J Neurooncol 119:243-51 (2014). PubMed: 24867209
  • Im S  et al. Hedgehog related protein expression in breast cancer: gli-2 is associated with poor overall survival. Korean J Pathol 47:116-23 (2013). IHC-P ; Human . PubMed: 23667370
  • Lezmi G  et al. FGF10 Signaling differences between type I pleuropulmonary blastoma and congenital cystic adenomatoid malformation. Orphanet J Rare Dis 8:130 (2013). IHC ; Human . PubMed: 24004862
  • Kaminagakura E  et al. Keratocyst of the buccal mucosa: case report and immunohistochemical comparative study with sporadic intraosseous keratocystic odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol 116:e387-92 (2013). IHC ; Human . PubMed: 23669203
  • Purmessur D  et al. Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development. Arthritis Res Ther 15:R122 (2013). IHC . PubMed: 24427812
  • Kim JY  et al. Prognostic Value of Sonic Hedgehog Protein Expression in Gastric Cancer. Jpn J Clin Oncol : (2012). IHC ; Human . PubMed: 22941587
  • Syn WK  et al. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease. Gut 61:1323-9 (2012). PubMed: 22427237
  • Schiapparelli P  et al. Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells. Cancer Lett 310:222-31 (2011). WB ; Human . PubMed: 21803487
  • McCann CK  et al. Inhibition of hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model. PLoS One 6:e28077 (2011). IHC-P ; Human . PubMed: 22140510
  • Tao Y  et al. Overexpression of Hedgehog signaling molecules and its involvement in triple-negative breast cancer. Oncol Lett 2:995-1001 (2011). PubMed: 22866163
  • Wang DH  et al. Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia. Gastroenterology 138:1810-22 (2010). PubMed: 20138038
  • Jung Y  et al. Signals from dying hepatocytes trigger growth of liver progenitors. Gut 59:655-65 (2010). PubMed: 20427400
  • Donnenberg VS  et al. Localization of CD44 and CD90 positive cells to the invasive front of breast tumors. Cytometry B Clin Cytom 78:287-301 (2010). IHC-P ; Human . PubMed: 20533389


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