Key features and details
- Rabbit polyclonal to Sorbitol Dehydrogenase
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Sorbitol Dehydrogenase antibody
See all Sorbitol Dehydrogenase primary antibodies
DescriptionRabbit polyclonal to Sorbitol Dehydrogenase
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Mouse, Rat, Human
Full length protein corresponding to Human Sorbitol Dehydrogenase.
Database link: Q00796
- HT29 cell lysate; mouse liver and kidney lysates.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
Our Abpromise guarantee covers the use of ab185705 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 38 kDa.|
|IHC-P||1/50 - 1/200.|
|ICC/IF||Use at an assay dependent concentration.|
FunctionConverts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
Tissue specificityExpressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
Sequence similaritiesBelongs to the zinc-containing alcohol dehydrogenase family.
Cellular localizationMitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
- Information by UniProt
- DHSO_HUMAN antibody
- L iditol 2 dehydrogenase antibody
- L-iditol 2-dehydrogenase antibody
All lanes : Anti-Sorbitol Dehydrogenase antibody (ab185705) at 1/500 dilution
Lane 1 : HT29 cell lysate
Lane 2 : mouse liver lysate
Lane 3 : mouse kidney lysate
Predicted band size: 38 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue labelling Sorbitol Dehydrogenase with ab185705 at 1/200. Magnification: 200x.
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab185705. Blue DAPI for nuclear staining.
ab185705 has been referenced in 1 publication.
- Wu Y et al. Quantitative Proteomic Analysis of Human Seminal Plasma from Normozoospermic and Asthenozoospermic Individuals. Biomed Res Int 2019:2735038 (2019). PubMed: 30984777