• Product name

    Anti-SorLA/SORL1 antibody - C-terminal
    See all SorLA/SORL1 primary antibodies
  • Description

    Rabbit polyclonal to SorLA/SORL1 - C-terminal
  • Host species

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Horse, Rhesus monkey
  • Immunogen

    Synthetic peptide within Human SorLA/SORL1 aa 2164-2214 (C terminal). The exact sequence is proprietary.
    Database link: Q92673

  • Positive control

    • WB: HeLa, HEK-293T and Jurkat whole cell lysates.
  • General notes

     This product was previously labelled as SorLA




Our Abpromise guarantee covers the use of ab226339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 248 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.
    • Tissue specificity

      Expressed mainly in brain, where it is most abundant in the cerebellum, cerebral cortex and the occipital pole; low expression in the putamen and the thalamus. According to PubMed:9157966, found in spinal cord, testis, liver, kidney and pancreas with detectable levels in placenta, lung and heart. According to PubMed:8940146, expressed in the prostate, ovary, thyroid and spleen, but not found in kidney, liver, lung, skeletal muscle, bone marrow and adrenals.
    • Sequence similarities

      Belongs to the SORL1 family.
      Contains 5 BNR repeats.
      Contains 1 EGF-like domain.
      Contains 6 fibronectin type-III domains.
      Contains 11 LDL-receptor class A domains.
      Contains 5 LDL-receptor class B repeats.
    • Post-translational

      The propeptide removed in the N-terminus may be cleaved by furin or homologous proteases.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • C11orf32 antibody
      • FLJ21930 antibody
      • FLJ39258 antibody
      • gp250 antibody
      • LDLR relative with 11 ligand binding repeats antibody
      • LDLR relative with 11 ligand-binding repeats antibody
      • Low density lipoprotein receptor relative with 11 ligand binding repeats antibody
      • Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody
      • LR 11 antibody
      • LR11 antibody
      • LRP 9 antibody
      • LRP9 antibody
      • Mosaic protein LR11 antibody
      • SORL 1 antibody
      • SORL_HUMAN antibody
      • SORL1 antibody
      • SorLA 1 antibody
      • SorLA antibody
      • SorLA-1 antibody
      • Sortilin related receptor antibody
      • Sortilin related receptor L(DLR class) A repeats containing antibody
      • Sortilin-related receptor antibody
      • Sorting protein related receptor containing LDLR class A repeats antibody
      • Sorting protein-related receptor containing LDLR class A repeats antibody
      see all


    • All lanes : Anti-SorLA/SORL1 antibody - C-terminal (ab226339) at 0.1 µg/ml

      Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
      Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
      Lane 3 : Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 248 kDa

      Exposure time: 3 seconds

      Cell lysates were prepared using NETN lysis buffer.


    ab226339 has not yet been referenced specifically in any publications.

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