Product nameAnti-SOSTDC1 antibody
See all SOSTDC1 primary antibodies
DescriptionRabbit polyclonal to SOSTDC1
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human SOSTDC1 (internal sequence).
- In Western Blot, this antibody gave a positive signal in human breast tissue lysate and in human, mouse and rat kidney tissue lysates.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 50% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab56079 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 23 kDa).|
|ELISA||Use at an assay dependent dilution.|
FunctionMay be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
Tissue specificityHighly expressed in kidney and weakly in lung.
Sequence similaritiesBelongs to the sclerostin family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
- Information by UniProt
- CDA019 antibody
- DKFZp564D206 antibody
- Ectodermal BMP inhibitor antibody
All lanes : Anti-SOSTDC1 antibody (ab56079) at 1 µg/ml
Lane 1 : Human kidney tissue lysate - total protein (ab30203)
Lane 2 : Human breast tissue lysate - total protein (ab30090)
Lane 3 : Kidney (Mouse) Tissue Lysate
Lane 4 : Kidney (Rat) Tissue Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 23 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
Exposure time: 4 minutes
The primary sequence of SOSTDC1 contains two potential glycosylation sites (Swissprot). This might explain the migration of this protein at a higher molecular weight than predicted.
ab56079 has not yet been referenced specifically in any publications.