Overview

  • Product name

    Sotalol hydrochloride, beta adrenoceptor antagonist
  • Description

    Non-selective beta adrenoceptor antagonist and potassium channel blocker
  • Biological description

    Non-selective beta adrenoceptor antagonist and potassium channel blocker (IC50 = 43 μM). Antiarrhythmic activity. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    959-24-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Liu W  et al. Sotalol permeability in cultured-cell, rat intestine, and PAMPA system. Pharm Res 29:1768-74 (2012). Read more (PubMed: 22350803) »
  • Jin Q  et al. Effects of procainamide and sotalol on restitution properties, dispersion of refractoriness, and ventricular fibrillation activation patterns in pigs. J Cardiovasc Electrophysiol 19:1090-7 (2008). Read more (PubMed: 18479337) »
  • Ishizaka T  et al. Comparison of electropharmacological effects of bepridil and sotalol in halothane-anesthetized dogs. Circ J 72:1003-11 (2008). Read more (PubMed: 18503230) »

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