Anti-SOX11 antibody (ab234996)
Key features and details
- Rabbit polyclonal to SOX11
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
-
Product name
Anti-SOX11 antibody
See all SOX11 primary antibodies -
Description
Rabbit polyclonal to SOX11 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Recombinant fragment corresponding to Human SOX11 aa 200-350.
Database link: P35716 -
Positive control
- WB: Rat and mouse brain tissue lysates. IHC-P: Human liver cancer and breast cancer tissues.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Protein G purified -
Purification notes
Purity >95% -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab234996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/20 - 1/200.
|
|
WB |
1/500 - 1/5000. Predicted molecular weight: 47 kDa.
|
Notes |
---|
IHC-P
1/20 - 1/200. |
WB
1/500 - 1/5000. Predicted molecular weight: 47 kDa. |
Target
-
Function
Probably important in the developing nervous system. May also have a role in tissue modeling during development. -
Tissue specificity
Expressed mainly in the nervous system. -
Sequence similarities
Contains 1 HMG box DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 6664 Human
- Entrez Gene: 20666 Mouse
- Entrez Gene: 84046 Rat
- Omim: 600898 Human
- SwissProt: P35716 Human
- SwissProt: Q7M6Y2 Mouse
- SwissProt: P0C1G9 Rat
- Unigene: 432638 Human
see all -
Alternative names
- MRD27 antibody
- SOX11 antibody
- SOX11_HUMAN antibody
see all
Images
-
Paraffin-embedded human breast cancer tissue stained for SOX11 using ab234996 at 1/100 dilution in immunohistochemical analysis.
-
Paraffin-embedded human liver cancer tissue stained for SOX11 using ab234996 at 1/100 dilution in immunohistochemical analysis.
-
All lanes : Anti-SOX11 antibody (ab234996) at 1/500 dilution
Lane 1 : Rat brain tissue lysate
Lane 2 : Mouse brain tissue lysate
Secondary
All lanes : Polyclonal Goat anti-rabbit IgG at 1/50000 dilution
Predicted band size: 47 kDa
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab234996 has been referenced in 1 publication.
- Wang Y et al. MicroRNA-31 inhibits papillary thyroid carcinoma cell biological progression by directly targeting SOX11 and regulating epithelial-to-mesenchymal transition, ERK and Akt signaling pathways. Eur Rev Med Pharmacol Sci 23:5863-5873 (2019). PubMed: 31298337