Recombinant Anti-SOX11 antibody [EPR8192] (ab134107)
- Datasheet
- References (5)
- Protocols
Overview
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Product name
Anti-SOX11 antibody [EPR8192]
See all SOX11 primary antibodies -
Description
Rabbit monoclonal [EPR8192] to SOX11 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IPmore details
Unsuitable for: Flow Cyt,ICC or IHC-P -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to residues in Human SOX11 (UniProt ID: P35716).
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Positive control
- WB: Human fetal brain and Y79 lysates.
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General notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
This product is a recombinant rabbit monoclonal antibody.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Dissociation constant (KD)
KD = 3.70 x 10 -11 M Learn more about KD -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.5% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR8192 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab134107 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 47 kDa). | |
| IP | 1/10 - 1/100. |
Target
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Function
Probably important in the developing nervous system. May also have a role in tissue modeling during development. -
Tissue specificity
Expressed mainly in the nervous system. -
Sequence similarities
Contains 1 HMG box DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 6664 Human
- Omim: 600898 Human
- SwissProt: P35716 Human
- Unigene: 432638 Human
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Alternative names
- MRD27 antibody
- SOX11 antibody
- SOX11_HUMAN antibody
see all
Images
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![Western blot - Anti-SOX11 antibody [EPR8192] (ab134107)](https://www.abcam.com/ps/products/134/ab134107/Images/ab134107-148287-anti-sox11-antibody-epr8192-western-blot.jpg)
Western blot - Anti-SOX11 antibody [EPR8192] (ab134107)All lanes : Anti-SOX11 antibody [EPR8192] (ab134107) at 1/1000 dilution
Lane 1 : Human fetal brain lysate
Lane 2 : Y79 lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 47 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted? -
![Other - Anti-SOX11 antibody [EPR8192] (ab134107)](https://www.abcam.com/ps/products/134/ab134107/Images/ab134107-148286-anti-sox11-antibody-epr8192.jpg)
Other - Anti-SOX11 antibody [EPR8192] (ab134107)
Datasheets and documents
References
This product has been referenced in:
- Smestad JA & Maher LJ Master regulator analysis of paragangliomas carrying SDHx, VHL, or MAML3 genetic alterations. BMC Cancer 19:619 (2019). Read more (PubMed: 31234811) »
- Ji Q et al. miR-223-3p Inhibits Human Osteosarcoma Metastasis and Progression by Directly Targeting CDH6. Mol Ther 26:1299-1312 (2018). Read more (PubMed: 29628305) »
