Anti-SOX9 antibody - ChIP Grade (ab3697)

Rabbit polyclonal SOX9 antibody. Validated in WB, IP, ELISA, IHC, ChIP, ICC/IF and tested in Mouse, Rat, Human. Cited in 41 publication(s). Independently reviewed in 8 review(s).

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ab3697 has been referenced in 42 publications.

  • Gallina D & Lincoln J Dynamic Expression Profiles of Sox9 in Embryonic, Post Natal, and Adult Heart Valve Cell Populations. Anat Rec (Hoboken) 302:108-116 (2019). PubMed: 30412364
  • Ma Z  et al. Autophagy promotes hepatic differentiation of hepatic progenitor cells by regulating the Wnt/ß-catenin signaling pathway. J Mol Histol 50:75-90 (2019). PubMed: 30604254
  • Navet B  et al. Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups. J Clin Med 7:N/A (2018). PubMed: 30413057
  • Chen Y  et al. Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Cell Tissue Res N/A:N/A (2018). PubMed: 30413887
  • Li S  et al. Exposure to fermentation supernatant of Staphylococcus aureus accelerated dedifferentiation of chondrocytes and production of antimicrobial peptides. J Orthop Res N/A:N/A (2017). PubMed: 28513981
  • Wa Q  et al. miR-30b regulates chondrogenic differentiation of mouse embryo-derived stem cells by targeting SOX9. Exp Ther Med 14:6131-6137 (2017). PubMed: 29285169
  • Kataruka S  et al. Mrhl Long Noncoding RNA Mediates Meiotic Commitment of Mouse Spermatogonial Cells by Regulating Sox8 Expression. Mol Cell Biol 37:N/A (2017). PubMed: 28461394
  • Ashraf S  et al. Role of RHEB in Regulating Differentiation Fate of Mesenchymal Stem Cells for Cartilage and Bone Regeneration. Int J Mol Sci 18:N/A (2017). IHC-P . PubMed: 28441755
  • Lapierre M  et al. Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors. Oncotarget 7:19693-708 (2016). IF . PubMed: 26930713
  • Tian-Zhong M  et al. Critical role of Emx2 in the pluripotency - differentiation transition in male gonocytes via regulation of FGF9/NODAL pathway. Reproduction 151:673-81 (2016). Mouse . PubMed: 27002001
  • Deng Y  et al. Yap1 Regulates Multiple Steps of Chondrocyte Differentiation during Skeletal Development and Bone Repair. Cell Rep 14:2224-2237 (2016). PubMed: 26923596
  • Ashkenazi S  et al. SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells. Oncotarget 7:30166-77 (2016). WB . PubMed: 26885752
  • Lu W  et al. CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model. Int J Mol Sci 17:N/A (2016). Rat . PubMed: 27690009
  • Yao Y  et al. MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia. Stem Cell Reports 7:249-62 (2016). WB ; Human . PubMed: 27509135
  • Huang L  et al. Rad9a is required for spermatogonia differentiation in mice. Oncotarget 7:86350-86358 (2016). IHC-P ; Mouse . PubMed: 27861152
  • Wang A  et al. Placental mesenchymal stromal cells rescue ambulation in ovine myelomeningocele. Stem Cells Transl Med 4:659-69 (2015). PubMed: 25911465
  • Shive HR  et al. Expression of KRASG12V in Zebrafish Gills Induces Hyperplasia and CXCL8-Associated Inflammation. Zebrafish 12:221-9 (2015). PubMed: 25798815
  • van den Akker GG  et al. Novel immortal human cell lines reveal subpopulations in the nucleus pulposus. Arthritis Res Ther 16:R135 (2014). WB . PubMed: 24972717
  • Malhotra GK  et al. The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. BMC Dev Biol 14:47 (2014). PubMed: 25527186
  • Bolt CC  et al. A distant downstream enhancer directs essential expression of Tbx18 in urogenital tissues. Dev Biol 392:483-93 (2014). PubMed: 24854998
  • Ahmed N  et al. Serum- and growth-factor-free three-dimensional culture system supports cartilage tissue formation by promoting collagen synthesis via Sox9-Col2a1 interaction. Tissue Eng Part A 20:2224-33 (2014). WB, IP ; Cow . PubMed: 24606204
  • Winkler T  et al. Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse. PLoS One 9:e98444 (2014). IHC-Fr ; Mouse . PubMed: 24892825
  • Yamamizu K  et al. SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1). Development 141:4254-66 (2014). PubMed: 25371362
  • Gillespie JR  et al. GSK-3ß function in bone regulates skeletal development, whole-body metabolism, and male life span. Endocrinology 154:3702-18 (2013). Mouse . PubMed: 23904355
  • Tümer E  et al. Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks. J Biol Chem 288:33813-23 (2013). ChIP . PubMed: 24121511
  • Lai LP  et al. Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A 110:19450-5 (2013). PubMed: 24218567
  • Danovi D  et al. A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1. PLoS One 8:e77053 (2013). WB . PubMed: 24204733
  • Dahia CL  et al. Shh signaling from the nucleus pulposus is required for the postnatal growth and differentiation of the mouse intervertebral disc. PLoS One 7:e35944 (2012). ICC/IF ; Mouse . PubMed: 22558278
  • Ditacchio L  et al. Transcription Factors ER71/ETV2 and SOX9 Participate in a Positive Feedback Loop in Fetal and Adult Mouse Testis. J Biol Chem 287:23657-66 (2012). ChIP ; Mouse . PubMed: 22613723
  • Shen J  et al. Arterial injury promotes medial chondrogenesis in Sm22 knockout mice. Cardiovasc Res 90:28-37 (2011). IHC-Fr ; Mouse . PubMed: 21183509
  • Aza-Carmona M  et al. SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer. Hum Mol Genet 20:1547-59 (2011). PubMed: 21262861
  • Yang J  et al. MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. FEBS Lett 585:2992-7 (2011). ChIP ; Mouse . PubMed: 21872590
  • Edwards GO  et al. Modelling condensation and the initiation of chondrogenesis in chick wing bud mesenchymal cells levitated in an ultrasound trap. Eur Cell Mater 19:1-12 (2010). ICC/IF ; Chicken . PubMed: 20077400
  • Takayama Y & Mizumachi K Inhibitory effect of lactoferrin on hypertrophic differentiation of ATDC5 mouse chondroprogenitor cells. Biometals 23:477-84 (2010). WB ; Mouse . PubMed: 20094900
  • Williams R  et al. Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage. PLoS One 5:e13246 (2010). ICC/IF ; Human . PubMed: 20976230
  • El-Helou V  et al. The cardiac neural stem cell phenotype is compromised in streptozotocin-induced diabetic cardiomyopathy. J Cell Physiol 220:440-9 (2009). WB, IHC-Fr ; Rat . PubMed: 19388005
  • Passeron T  et al. Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. J Clin Invest 119:954-63 (2009). PubMed: 19273910
  • Mukhopadhyay P  et al. Suppression of chondrogenesis by Id helix-loop-helix proteins in murine embryonic orofacial tissue. Differentiation 77:462-72 (2009). PubMed: 19349107
  • Khan IM  et al. Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential. Osteoarthritis Cartilage 17:518-28 (2009). PubMed: 19010695
  • Passeron T  et al. SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation. Proc Natl Acad Sci U S A 104:13984-9 (2007). PubMed: 17702866
  • Chen Y  et al. Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. J Biol Chem 282:526-33 (2007). WB ; Mouse . PubMed: 17085452
  • Ottolenghi C  et al. Foxl2 is required for commitment to ovary differentiation. Hum Mol Genet 14:2053-62 (2005). PubMed: 15944199

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