Anti-SP1 (phospho T453) antibody (ab59257)

Rabbit polyclonal SP1 (phospho T453) antibody. Validated in WB, ELISA, IHC, ChIP, ICC/IF and tested in Mouse, Rat, Human. Cited in 18 publication(s). Independently reviewed in 6 review(s).

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ab59257 has been referenced in 18 publications.

  • Román AC  et al. Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish. Genome Biol 19:55 (2018). PubMed: 29695303
  • Lv W  et al. KIAA0101 inhibition suppresses cell proliferation and cell cycle progression by promoting the interaction between p53 and Sp1 in breast cancer. Biochem Biophys Res Commun 503:600-606 (2018). PubMed: 29902451
  • Nandi SS & Mishra PK H2S and homocysteine control a novel feedback regulation of cystathionine beta synthase and cystathionine gamma lyase in cardiomyocytes. Sci Rep 7:3639 (2017). WB, ChIP, EMSA ; Mouse . PubMed: 28623294
  • Zu X  et al. TGF-ß1 induces HMGA1 expression in human breast cancer cells: implications of the involvement of HMGA1 in TGF-ß signaling. Int J Mol Med 35:693-701 (2015). PubMed: 25572132
  • Zhao J  et al. Sp1-CD147 positive feedback loop promotes the invasion ability of ovarian cancer. Oncol Rep 34:67-76 (2015). PubMed: 25998266
  • Shimoyama S  et al. Dephosphorylation of Sp1 at Ser-59 by protein phosphatase 2A (PP2A) is required for induction of CYP1A1 transcription after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin or omeprazole. Biochim Biophys Acta 1839:107-15 (2014). PubMed: 24382322
  • Du Y  et al. NF-?B and enhancer-binding CREB protein scaffolded by CREB-binding protein (CBP)/p300 proteins regulate CD59 protein expression to protect cells from complement attack. J Biol Chem 289:2711-24 (2014). Human . PubMed: 24338025
  • Wutthisathapornchai A  et al. Multiple E-boxes in the distal promoter of the rat pyruvate carboxylase gene function as a glucose-responsive element. PLoS One 9:e102730 (2014). WB . PubMed: 25054881
  • Cao HH  et al. A molecular prognostic model predicts esophageal squamous cell carcinoma prognosis. PLoS One 9:e106007 (2014). IHC-P ; Human . PubMed: 25153136
  • Grell AS  et al. Regulatory mechanism of endothelin receptor B in the cerebral arteries after focal cerebral ischemia. PLoS One 9:e113624 (2014). WB . PubMed: 25479176
  • Hamada S  et al. The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2. J Cell Physiol 227:729-38 (2012). Human . PubMed: 21465479
  • Cailotto F  et al. Calcium input potentiates the transforming growth factor (TGF)-beta1-dependent signaling to promote the export of inorganic pyrophosphate by articular chondrocyte. J Biol Chem 286:19215-28 (2011). WB . PubMed: 21471198
  • Lin HH  et al. Heme Oxygenase-1/Carbon Monoxide Induces Vascular Endothelial Growth Factor Expression via p38 Kinase-dependent Activation of Sp1. J Biol Chem 286:3829-38 (2011). WB, ICC/IF, IHC-P ; Mouse, Rat . PubMed: 21115498
  • Yi T  et al. Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression. J Biol Chem 285:17811-20 (2010). ChIP ; Mouse . PubMed: 20375015
  • Murthy S  et al. Rac1-mediated Mitochondrial H2O2 Generation Regulates MMP-9 Gene Expression in Macrophages via Inhibition of SP-1 and AP-1. J Biol Chem 285:25062-73 (2010). WB ; Mouse . PubMed: 20529870
  • Hassan M  et al. Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways. Hepatology 49:1469-82 (2009). WB ; Human . PubMed: 19235829
  • Zhong Z  et al. Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells. J Clin Invest 119:3437-49 (2009). WB ; Mouse . PubMed: 19841542
  • Saha A  et al. The role of Sp1 in IL-1beta and H. pylori-mediated regulation of H,K-ATPase gene transcription. Am J Physiol Gastrointest Liver Physiol 295:G977-86 (2008). WB ; Human . PubMed: 18772363

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