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ab37977 has been referenced in 18 publications.

  • Kreitzburg KM  et al. FTY720 enhances the anti-tumor activity of carboplatin and tamoxifen in a patient-derived xenograft model of ovarian cancer. Cancer Lett 436:75-86 (2018). PubMed: 30120964
  • Shi WN  et al. Overexpression of SphK2 contributes to ATRA resistance in colon cancer through rapid degradation of cytoplasmic RXRa by K48/K63-linked polyubiquitination. Oncotarget 8:39605-39617 (2017). WB . PubMed: 28465486
  • Di Pardo A  et al. Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease. Sci Rep 7:5280 (2017). WB . PubMed: 28706199
  • Morchang A  et al. RNAi screen reveals a role of SPHK2 in dengue virus-mediated apoptosis in hepatic cell lines. PLoS One 12:e0188121 (2017). PubMed: 29145490
  • Nojima H  et al. Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate. J Hepatol 64:60-8 (2016). PubMed: 26254847
  • Fu P  et al. Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. J Biol Chem 291:27187-27203 (2016). PubMed: 27864331
  • Testai FD  et al. Changes in the metabolism of sphingolipids after subarachnoid hemorrhage. J Neurosci Res 93:796-805 (2015). WB ; Human . PubMed: 25597763
  • Panneer Selvam S  et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Sci Signal 8:ra58 (2015). WB ; Human . PubMed: 26082434
  • Ceccom J  et al. Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease. Acta Neuropathol Commun 2:12 (2014). WB ; Human . PubMed: 24468113
  • Novgorodov SA  et al. Essential roles of neutral ceramidase and sphingosine in mitochondrial dysfunction due to traumatic brain injury. J Biol Chem 289:13142-54 (2014). WB, IP ; Mouse . PubMed: 24659784
  • Sheng R  et al. Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons. J Biol Chem 289:20845-20857 (2014). WB ; Mouse . PubMed: 24928515
  • Awojoodu AO  et al. Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD. Blood 124:1941-50 (2014). PubMed: 25075126
  • Yamane D  et al. Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation. Nat Med 20:927-35 (2014). WB . PubMed: 25064127
  • Harijith A  et al. Sphingosine Kinase 1 Deficiency Confers Protection against Hyperoxia-Induced Bronchopulmonary Dysplasia in a Murine Model: Role of S1P Signaling and Nox Proteins. Am J Pathol 183:1169-82 (2013). PubMed: 23933064
  • Lucki NC  et al. Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Mol Endocrinol 26:228-43 (2012). PubMed: 22261821
  • Kim M  et al. Isoflurane activates intestinal sphingosine kinase to protect against bilateral nephrectomy-induced liver and intestine dysfunction. Am J Physiol Renal Physiol 300:F167-76 (2011). WB ; Mouse . PubMed: 20962114
  • Kim M  et al. Isoflurane activates intestinal sphingosine kinase to protect against renal ischemia-reperfusion-induced liver and intestine injury. Anesthesiology 114:363-73 (2011). PubMed: 21245730
  • Aydin M  et al. The sphingosine-1-phosphate pathway is upregulated in response to partial urethral obstruction in male rats and activates RhoA/Rho-kinase signalling. BJU Int 106:562-71 (2010). PubMed: 20128782

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