Anti-SPHKAP antibody (ab155225)
Key features and details
- Rabbit polyclonal to SPHKAP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SPHKAP antibody -
Description
Rabbit polyclonal to SPHKAP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Recombinant protein fragment, corresponding to a region within amino acids 1-219 of Human SPHKAP (UniProt ID: Q2M3C7).
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Positive control
- NT2D1, IMR32 and MCF7 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab155225 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. |
Target
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Function
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. -
Tissue specificity
Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain. -
Sequence similarities
Belongs to the AKAP110 family. -
Domain
RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer. -
Cellular localization
Cytoplasm. Colocalizes with SPHK1 in the cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 80309 Human
- Entrez Gene: 77629 Mouse
- Omim: 611646 Human
- SwissProt: Q2M3C7 Human
- SwissProt: Q6NSW3 Mouse
- Unigene: 436306 Human
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Alternative names
- A-kinase anchor protein SPHKAP antibody
- DKFZp781H143 antibody
- DKFZp781J171 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab155225 has not yet been referenced specifically in any publications.