Overview

  • Product name

  • Description

    Rabbit polyclonal to Spic
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish, Spider monkey
  • Immunogen

    Synthetic peptide corresponding to a region within the C-terminal amino acids 148-197 (EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI) of Human Spic (NP_689536.1).

  • Positive control

    • Human Renal ACHN Cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 29 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
  • Tissue specificity

    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
  • Sequence similarities

    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • AU019198 antibody
    • C76795 antibody
    • MGC40611 antibody
    • MGC80555 antibody
    • Prf antibody
    • Pu.1 related factor antibody
    • Spi C antibody
    • Spi C transcription factor antibody
    • Spi-C transcription factor (Spi-1/PU.1 related) antibody
    • spiC antibody
    • SPIC_HUMAN antibody
    • Transcription factor Spi-C antibody
    see all

Images

  • Anti-Spic antibody (ab118953) at 1 µg/ml + ACHN Cell lysate at 10 µg

    Predicted band size: 29 kDa



    Gel Concentration: 12%

References

ab118953 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab118953.
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