Overview

  • Product name

  • Description

    Rabbit polyclonal to Spic
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human Spic aa 1-131. The exact sequence is proprietary.
    Database link: Q8N5J4

  • Positive control

    • Jurkat, Raji and NCI-H929 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab183857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 29 kDa.

Target

  • Function

    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
  • Tissue specificity

    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
  • Sequence similarities

    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • AU019198 antibody
    • C76795 antibody
    • MGC40611 antibody
    • MGC80555 antibody
    • Prf antibody
    • Pu.1 related factor antibody
    • Spi C antibody
    • Spi C transcription factor antibody
    • Spi-C transcription factor (Spi-1/PU.1 related) antibody
    • spiC antibody
    • SPIC_HUMAN antibody
    • Transcription factor Spi-C antibody
    see all

Images

  • All lanes : Anti-Spic antibody (ab183857) at 1/5000 dilution

    Lane 1 : Jurkat whole cell lysate/extract
    Lane 2 : Raji whole cell lysate/extract
    Lane 3 : NCI-H929 whole cell lysate/extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 29 kDa

References

ab183857 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab183857.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up