• Product name
    Anti-SPIN90 antibody [2614C1a]
    See all SPIN90 primary antibodies
  • Description
    Mouse monoclonal [2614C1a] to SPIN90
  • Host species
  • Tested applications
    Suitable for: WB, Dot blotmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SPIN90.

  • General notes

    Previously labelled as NCKIPSD.



Our Abpromise guarantee covers the use of ab58676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 79 kDa.
Dot blot Use at an assay dependent dilution.


  • Function
    Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion.
  • Tissue specificity
    Highest expression in heart, brain, skeletal muscle, kidney and liver. Lower levels in placenta, lung, small intestine and leukocytes. Weak expression in colon, thymus and spleen.
  • Involvement in disease
    Note=A chromosomal aberration involving NCKIPSD/AF3p21 is found in therapy-related leukemia. Translocation t(3;11)(p21;q23) with MLL.
  • Sequence similarities
    Contains 1 SH3 domain.
  • Cellular localization
    Nucleus. Colocalizes with DRF1 at membrane ruffles, and with Nck at Z-disks in mature cardiac myocytes.
  • Information by UniProt
  • Database links
  • Alternative names
    • 54 kDa VacA-interacting protein antibody
    • 54 kDa vimentin-interacting protein antibody
    • 90 kDa SH3 protein interacting with Nck antibody
    • AF3p21 antibody
    • dia interacting protein antibody
    • Dia-interacting protein 1 antibody
    • Diaphanous protein-interacting protein antibody
    • DIP antibody
    • DIP-1 antibody
    • DIP1 antibody
    • NCK interacting protein with SH3 domain antibody
    • NCK-interacting protein with SH3 domain antibody
    • Nckipsd antibody
    • ORF1 antibody
    • SH3 adapter protein SPIN90 antibody
    • SH3 protein interacting with Nck 90 kDa antibody
    • SPIN90 antibody
    • SPN90_HUMAN antibody
    • VIP54 antibody
    • WASLBP antibody
    • WASP-interacting SH3-domain protein antibody
    • WISH antibody
    • wiskott- Aldrich syndrome protein-interacting protein antibody
    • Wiskott-Aldrich syndrome protein-interacting protein antibody
    see all



ab58676 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A


Thank you for reply, and I apologize again for the variability in the results with this antibody. I am sending a free of charge replacement vial on the order ***. We currently are out of stock of ab58676, so the expected delivery date is December 14. All of the vials of this antibody that we have previously sold were from the same production batch, so I am expecting that this is a problem with the specific vial and a new vial will work better. Please keep me updated about the results using the replacement vial, and let me know if there is anything else that we can do for you.

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Thank you for contacting us and letting us know about the problem with this antibody. I am sorry to hear that this new lot is not working as expected. We do guarantee all our products to worked in tested species and applications for up to 6 months after purchase, so I would be happy to send a new vial of ab58676 or alternatively issue a credit or refund. Please let me know which you prefer, and if you have any questions.

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