Key features and details
- Rabbit polyclonal to Spry-2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Spry-2 antibody
See all Spry-2 primary antibodies
DescriptionRabbit polyclonal to Spry-2
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Monkey, Orangutan
Synthetic peptide corresponding to Human Spry-2 (internal sequence).
Database link: O43597
- Human liver and kidney tissues; Human kidney clear cell tumor tissue.
Previously labelled as Sprouty 2.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191284 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 µg/ml.|
FunctionMay function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Sequence similaritiesBelongs to the sprouty family.
Contains 1 SPR (sprouty) domain.
DomainThe Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
Cellular localizationCytoplasm > cytoskeleton. Cell projection > ruffle membrane. Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated ith EGF.
- Information by UniProt
- hSPRY 2 antibody
- hSPRY2 antibody
- MGC23039 antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling Spry-2 with ab191284 at 10 µg/ml.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labeling Spry-2 with ab191284 at 10 µg/ml.
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human kidney clear cell tumor labeling Spry-2 with ab191284 at 1/250 dilution. Secondary antibody: Alexa Fluoro 488 secondary at 1/500 dilution. Staining: green = Spry-2, Blue = DAPI, red= VHL.
ab191284 has not yet been referenced specifically in any publications.