Product nameAnti-SPTY2D1 antibody
See all SPTY2D1 primary antibodies
DescriptionRabbit polyclonal to SPTY2D1
Tested applicationsSuitable for: WBmore details
Unsuitable for: IP
Species reactivityReacts with: Human
Predicted to work with: Mouse, Sheep, Rabbit, Horse, Cow, Dog, Chimpanzee, Macaque monkey, Rhesus monkey, Gorilla, Orangutan
Synthetic peptide within Human SPTY2D1 aa 75-125 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary. from Isoform 3.
Database link: Q68D10.3
- HeLa and 293T whole cell lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab215722 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/5000. Predicted molecular weight: 76 kDa.|
RelevanceFunction: Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). Modulates RNA polymerase 1-mediated transcription (By similarity). Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026). Similarity: Belongs to the SPT2 family. Domain: The acidic C-terminal domain mediates interaction with histone H3/H4 complexes.
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ab215722 has not yet been referenced specifically in any publications.