Overview

  • Product name

  • Description

    Rabbit polyclonal to Spy1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human Spy1 aa 100-130 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: Q5MJ70

  • Positive control

    • Rat testis tissue
  • General notes

    Previously labelled as SPDYA. 

Properties

Applications

Our Abpromise guarantee covers the use of ab218208 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Relevance

    Spy1 (speedy homolog A (Drosophila)) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. Spy1 can activate CDK2 without promoting CDK2 phosphorylation. Spy1 mediates cell survival during the DNA damage process through activation of CDK2.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • hSpy/Ringo A antibody
    • MGC110856 antibody
    • MGC57218 antibody
    • OTTHUMP00000082662 antibody
    • OTTHUMP00000082663 antibody
    • OTTHUMP00000082664 antibody
    • Rapid inducer of G2/M progression in oocytes A antibody
    • RINGO A antibody
    • RINGO3 antibody
    • SPDY1 antibody
    • SPDYA antibody
    • Speedy A antibody
    • Speedy homolog 1 (Drosophila) antibody
    • Speedy homolog A antibody
    • Speedy homolog A (Xenopus laevis) antibody
    • Speedy-1 antibody
    • SPY1 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of Rat testis tissue labeling Spy1 with ab218208 at a 1/200 dilution, followed by conjugation to a secondary antibody and DAB staining.

References

ab218208 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab218208.
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