Validated using a knockout cell line
Recombinant
RabMAb

Recombinant Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012)

Publishing research using ab109012? Please let us know so that we can cite the reference in this datasheet.

ab109012 has been referenced in 66 publications.

  • Li Y  et al. CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway. J Lipid Res N/A:N/A (2019). PubMed: 30662007
  • Yang Y  et al. Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma. Cell Death Dis 10:41 (2019). PubMed: 30674868
  • Zhuang H  et al. Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma. Cell Death Dis 10:192 (2019). PubMed: 30804330
  • Diao C  et al. Aged kidneys are refractory to autophagy activation in a rat model of renal ischemia-reperfusion injury. Clin Interv Aging 14:525-534 (2019). PubMed: 30880933
  • Ren Z  et al. Inhibition of human glioblastoma cell invasion involves PION@E6 mediated autophagy process. Cancer Manag Res 11:2643-2652 (2019). PubMed: 31015768
  • Zhang Z  et al. circARF3 Alleviates Mitophagy-Mediated Inflammation by Targeting miR-103/TRAF3 in Mouse Adipose Tissue. Mol Ther Nucleic Acids 14:192-203 (2019). PubMed: 30623853
  • Sinkevicius KW  et al. RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory. Dis Model Mech 11:N/A (2018). PubMed: 29752287
  • Ganesan S  et al. Prolonged environment-induced hyperthermia alters autophagy in oxidative skeletal muscle in Sus scrofa. J Therm Biol 74:160-169 (2018). PubMed: 29801622
  • Kustermann M  et al. Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo. Autophagy 14:1911-1927 (2018). PubMed: 30010465
  • Jia B  et al. Autophagy inhibitor chloroquine induces apoptosis of cholangiocarcinoma cells via endoplasmic reticulum stress. Oncol Lett 16:3509-3516 (2018). PubMed: 30127955
  • Xia W  et al. Parkin Modulates ERRa/eNOS Signaling Pathway in Endothelial Cells. Cell Physiol Biochem 49:2022-2034 (2018). PubMed: 30244249
  • Lei H  et al. Inhibiting TrxR suppresses liver cancer by inducing apoptosis and eliciting potent antitumor immunity. Oncol Rep 40:3447-3457 (2018). PubMed: 30272318
  • Bendorius M  et al. The Mitochondrion-lysosome Axis in Adaptive and Innate Immunity: Effect of Lupus Regulator Peptide P140 on Mitochondria Autophagy and NETosis. Front Immunol 9:2158 (2018). PubMed: 30319621
  • González Coraspe JA  et al. Biochemical and pathological changes result from mutated Caveolin-3 in muscle. Skelet Muscle 8:28 (2018). PubMed: 30153853
  • Meng D  et al. Carvedilol attenuates liver fibrosis by suppressing autophagy and promoting apoptosis in hepatic stellate cells. Biomed Pharmacother 108:1617-1627 (2018). PubMed: 30372864
  • Wang F  et al. Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival. Sci Rep 8:16820 (2018). PubMed: 30429537
  • Zhang P  et al. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis 9:1145 (2018). PubMed: 30451833
  • Zhang K  et al. Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy. Nat Commun 9:5129 (2018). PubMed: 30510196
  • Kang C  et al. Baicalin alleviates 6-hydroxydopamine-induced neurotoxicity in PC12 cells by down-regulation of microRNA-192-5p. Brain Res N/A:N/A (2018). PubMed: 30552896
  • Feng XL  et al. Suberoylanilide Hydroxamic Acid Triggers Autophagy by Influencing the mTOR Pathway in the Spinal Dorsal Horn in a Rat Neuropathic Pain Model. Neurochem Res N/A:N/A (2018). PubMed: 30560396
  • Zhang X  et al. Blocking Autophagy in Cancer-Associated Fibroblasts Supports Chemotherapy of Pancreatic Cancer Cells. Front Oncol 8:590 (2018). PubMed: 30568920
  • Bartolome F  et al. Amyloid ß-induced impairments on mitochondrial dynamics, hippocampal neurogenesis, and memory are restored by phosphodiesterase 7 inhibition. Alzheimers Res Ther 10:24 (2018). WB . PubMed: 29458418
  • Flores-Costa R  et al. The soluble guanylate cyclase stimulator IW-1973 prevents inflammation and fibrosis in experimental non-alcoholic steatohepatitis. Br J Pharmacol 175:953-967 (2018). PubMed: 29281143
  • Wang P  et al. Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury. Oncotarget 9:8427-8440 (2018). PubMed: 29492205
  • Guo D  et al. Resveratrol protects early brain injury after subarachnoid hemorrhage by activating autophagy and inhibiting apoptosis mediated by the Akt/mTOR pathway. Neuroreport 29:368-379 (2018). PubMed: 29360689
  • Zheng YY  et al. Autophagy activation by Jiang Zhi Granule protects against metabolic stress-induced hepatocyte injury. World J Gastroenterol 24:992-1003 (2018). PubMed: 29531463
  • Sun Y  et al. SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins. Sci Rep 8:5287 (2018). PubMed: 29588492
  • Sun D  et al. bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats. Cell Death Dis 9:172 (2018). WB ; Rat . PubMed: 29416039
  • Ladds MJGW  et al. Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib. PLoS One 13:e0195956 (2018). PubMed: 29684045
  • Peng S  et al. Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy. Front Pharmacol 9:438 (2018). PubMed: 29773990
  • Brownstein AJ  et al. Heat stress causes dysfunctional autophagy in oxidative skeletal muscle. Physiol Rep 5:N/A (2017). WB, IHC-P . PubMed: 28646096
  • Du A  et al. Suppression of CHRN endocytosis by carbonic anhydrase CAR3 in the pathogenesis of myasthenia gravis. Autophagy 13:1981-1994 (2017). PubMed: 28933591
  • He Z  et al. Autophagy protects auditory hair cells against neomycin-induced damage. Autophagy 13:1884-1904 (2017). PubMed: 28968134
  • Mahrouf-Yorgov M  et al. Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties. Cell Death Differ 24:1224-1238 (2017). Flow Cyt ; Human . PubMed: 28524859
  • Cen WJ  et al. Iron overload induces G1 phase arrest and autophagy in murine preosteoblast cells. J Cell Physiol N/A:N/A (2017). PubMed: 29244196
  • Mu Y  et al. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep 7:43475 (2017). PubMed: 28276438
  • Maueröder C  et al. Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide. Front Immunol 8:16 (2017). PubMed: 28191006
  • Deng YP  et al. Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells. Exp Ther Med 14:753-758 (2017). PubMed: 28672995
  • Huang Z  et al. MicroRNA-21 protects against cardiac hypoxia/reoxygenation injury by inhibiting excessive autophagy in H9c2 cells via the Akt/mTOR pathway. J Cell Mol Med 21:467-474 (2017). PubMed: 27680680
  • Zhang L  et al. Fucoxanthin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE and Nrf2-autophagy pathways. Sci Rep 7:46763 (2017). WB . PubMed: 28429775
  • Matos L  et al. Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis. Oxid Med Cell Longev 2017:3793817 (2017). PubMed: 28280523
  • Sainz de la Maza D  et al. Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency. Oxid Med Cell Longev 2017:4745252 (2017). ICC/IF ; Mouse . PubMed: 28757909
  • Wang ME  et al. Increasing Dietary Medium-Chain Fatty Acid Ratio Mitigates High-fat Diet-Induced Non-Alcoholic Steatohepatitis by Regulating Autophagy. Sci Rep 7:13999 (2017). PubMed: 29070903
  • Pan T  et al. Abnormal CYP11A1 gene expression induces excessive autophagy, contributing to the pathogenesis of preeclampsia. Oncotarget 8:89824-89836 (2017). PubMed: 29163791
  • Brun S  et al. Assessing Autophagy in Sciatic Nerves of a Rat Model that Develops Inflammatory Autoimmune Peripheral Neuropathies. Cells 6:N/A (2017). WB, IF ; Rat . PubMed: 28927011
  • Wu Q  et al. miR-1224-5p Mediates Mitochondrial Damage to Affect Silica-Induced Pulmonary Fibrosis by Targeting BECN1. Int J Mol Sci 18:N/A (2017). PubMed: 29112159
  • Yang C  et al. A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells. J Transl Med 15:211 (2017). PubMed: 29052509
  • Li Y  et al. Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells. Int J Mol Med 40:1405-1414 (2017). PubMed: 28949381
  • Ma B  et al. Long non-coding RNA MEG3 contributes to cisplatin-induced apoptosis via inhibition of autophagy in human glioma cells. Mol Med Rep 16:2946-2952 (2017). PubMed: 28677749
  • Chen M  et al. Lipopolysaccharide mediates hepatic stellate cell activation by regulating autophagy and retinoic acid signaling. Autophagy 13:1813-1827 (2017). PubMed: 29160747
  • Lu K  et al. NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction. Cancer Res 77:2881-2892 (2017). PubMed: 28416489
  • Tang F  et al. SBI0206965, a novel inhibitor of Ulk1, suppresses non-small cell lung cancer cell growth by modulating both autophagy and apoptosis pathways. Oncol Rep 37:3449-3458 (2017). PubMed: 28498429
  • Taniguchi K  et al. An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. J Cell Biol 216:3981-3990 (2017). PubMed: 29021220
  • Matos L  et al. Erratum to "Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis". Oxid Med Cell Longev 2017:9172085 (2017). PubMed: 29147466
  • Zhang J  et al. Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells. Cell Death Dis 8:e2954 (2017). PubMed: 28749469
  • Li B  et al. Role of autophagy on bone marrow mesenchymal stem-cell proliferation and differentiation into neurons. Mol Med Rep 13:1413-9 (2016). PubMed: 26676567
  • Gentry EG  et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci 36:1316-23 (2016). PubMed: 26818518
  • Fiuza-Luces C  et al. Muscle Signaling in Exercise Intolerance: Insights from the McArdle Mouse Model. Med Sci Sports Exerc N/A:N/A (2016). WB . PubMed: 27031745
  • Bühler A  et al. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci 17:N/A (2016). PubMed: 26840306
  • Navarro-Yepes J  et al. Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways. Mol Neurobiol 53:5229-51 (2016). PubMed: 26409479
  • Ulasov IV  et al. Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy. Oncotarget 6:3977-87 (2015). WB . PubMed: 25738357
  • Hu B  et al. Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway. Autophagy 11:503-15 (2015). PubMed: 25714412
  • Perez SE  et al. Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aß and tau pathology. J Neuropathol Exp Neurol 74:345-58 (2015). PubMed: 25756588
  • Xia M  et al. Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus. Oncotarget 5:3907-18 (2014). WB . PubMed: 25004098
  • Xia M  et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol 88:5152-64 (2014). PubMed: 24574393
  • Xiong Y  et al. ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis. Autophagy 10:2223-38 (2014). PubMed: 25484082

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