Key features and details
- Potent, selective β3 adrenoceptor antagonist
- CAS Number: 1135278-41-9
- Purity: > 99%
- Soluble in water to 10 mM and DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameSR 59230A hydrochloride, beta3 adrenoceptor antagonist
DescriptionPotent, selective β3 adrenoceptor antagonist
Potent, selective β3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for β3, β1 and β2, respectively). Orally active in vivo.
Chemical name(2S)-1-(2-Ethylphenoxy)-3-[[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]-2-propanol hydrochloride
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 10 mM and DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.With gentle heating this product rapidly dissolves in water to make a 100mM solution, however the product will quickly come out of solution on cooling. We therefore recommend making 100mM solutions in DMSO unless they are to be used immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141135 has not yet been referenced specifically in any publications.