Key features and details
- Rabbit polyclonal to SR protein repeat/SRSF6
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-SR protein repeat/SRSF6 antibody
See all SR protein repeat/SRSF6 primary antibodies
DescriptionRabbit polyclonal to SR protein repeat/SRSF6
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
- IHC-P: Human gastrointestinal, prostate, tonsil and skeletal muscle tissues. WB: MOLT-4 and NIH/3T3 cell lysates.
This product was previously labelled as SR protein repeat
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab244425 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 40 kDa.|
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionPlays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
Sequence similaritiesBelongs to the splicing factor SR family.
Contains 2 RRM (RNA recognition motif) domains.
modificationsExtensively phosphorylated on serine residues in the RS domain.
- Information by UniProt
- arginine/serine-rich 6 antibody
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Paraffin-embedded human gastrointestinal tissue stained for SR protein repeat/SRSF6 using ab244425 at 1/50 dilution in immunohistochemical analysis.
Anti-SR protein repeat/SRSF6 antibody (ab244425) at 0.4 µg/ml + MOLT-4 (human lymphoblastic leukemia cell line) cell lysate
Predicted band size: 40 kDa
Paraffin-embedded human prostate tissue stained for SR protein repeat/SRSF6 using ab244425 at 1/50 dilution in immunohistochemical analysis.
All lanes : Anti-SR protein repeat/SRSF6 antibody (ab244425) at 0.4 µg/ml
Lane 1 : NIH/3T3 (mouse embyro fibroblast cell line) cell lysate
Lane 2 : NBT-II cell lysate
Predicted band size: 40 kDa
Immunohistochemical staining of human skeletal muscle shows moderate nuclear positivity in myocytes.
Paraffin-embedded human tonsil tissue stained for SR protein repeat/SRSF6 using ab244425 at 1/50 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab244425 has not yet been referenced specifically in any publications.