Overview

  • Product name

    Anti-SR protein repeat/SRSF6 antibody [EPR9231]
    See all SR protein repeat/SRSF6 primary antibodies
  • Description

    Rabbit monoclonal [EPR9231] to SR protein repeat/SRSF6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human SR protein repeat/SRSF6 aa 150-250. The exact sequence is proprietary.

  • Positive control

    • K562, Jurkat and HeLa whole cell lysate (ab150035); Human gastric carcinoma tissue.
  • General notes

     

     

     This product was previously labelled as SR protein repeat

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR9231
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab140623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 40 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10.
    • Sequence similarities

      Belongs to the splicing factor SR family.
      Contains 2 RRM (RNA recognition motif) domains.
    • Post-translational
      modifications

      Extensively phosphorylated on serine residues in the RS domain.
    • Cellular localization

      Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • arginine/serine-rich 6 antibody
      • B52 antibody
      • Epididymis secretory protein Li 91 antibody
      • fc17h09 antibody
      • HEL S 91 antibody
      • MGC128807 antibody
      • MGC5045 antibody
      • Pre mRNA splicing factor SRP55 antibody
      • Pre-mRNA-splicing factor SRP55 antibody
      • Serine/arginine-rich splicing factor 6 antibody
      • SFRS6 antibody
      • Splicing factor antibody
      • Splicing factor arginine/serine rich 55 kDa antibody
      • Splicing factor arginine/serine rich 6 antibody
      • SR splicing factor 6 antibody
      • SRP55 antibody
      • SRSF6 antibody
      • SRSF6_HUMAN antibody
      • wu:faa54g02 antibody
      • wu:fc17h09 antibody
      • zgc:103497 antibody
      see all

    Images

    • All lanes : Anti-SR protein repeat/SRSF6 antibody [EPR9231] (ab140623) at 1/1000 dilution

      Lane 1 : K562 cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 40 kDa

    • Immunohistochemical analysis of paraffin-embedded Human gastric carcinoma tissue labelling SR protein repeat/SRSF6 with ab140623 at 1/50 dilution.

    • Immunohistochemical analysis of paraffin embedded Human Ovarian carcinoma tissue using ab140623 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded normal Human uterus tissue using ab140623 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded normal Human brain tissue using ab140623 showing +ve staining.

    • Immunohistochemical analysis of paraffin embedded Human Breast carcinoma tissue using ab140623 showing +ve staining.

    References

    This product has been referenced in:

    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140623.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up