Overview

  • Product name

  • Description

    Rabbit polyclonal to SR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-198 of Human SR1 (Uniprot ID P30626)

  • Positive control

    • 293T, A431, H1299, HeLaS3, Raji cells; Molt-4 and mouse heart whole cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab155015 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 21 kDa.

Target

  • Function

    Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
  • Tissue specificity

    Detected in cardiac myocytes.
  • Sequence similarities

    Contains 4 EF-hand domains.
  • Cellular localization

    Cytoplasm. Sarcoplasmic reticulum membrane. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
  • Information by UniProt
  • Database links

  • Alternative names

    • 22 kDa protein antibody
    • Calcium binding protein amplified in mutlidrug resistant cells antibody
    • CP 22 antibody
    • CP-22 antibody
    • CP22 antibody
    • SCN antibody
    • Sorcin (class 4 gene) antibody
    • Sorcin antibody
    • SORCN_HUMAN antibody
    • SRI antibody
    • V19 antibody
    see all

Images

  • All lanes : Anti-SR1 antibody (ab155015) at 1/500 dilution

    Lane 1 : WT HeLa cell extract
    Lane 2 : SR1 Knockout HeLa cell extracts

    Lysates/proteins at 30 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG

    Predicted band size: 21 kDa

  • Anti-SR1 antibody (ab155015) at 1/500 dilution + Molt4 whole cell lysate at 30 µg

    Predicted band size: 21 kDa



    15% SDS PAGE
  • Anti-SR1 antibody (ab155015) at 1/500 dilution + mouse heart whole cell lysate at 50 µg

    Predicted band size: 21 kDa



    12% SDS PAGE

References

ab155015 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab155015.
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