Key features and details
- Rabbit polyclonal to SR1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Horse, Cow, Dog, Human, Chimpanzee, Monkey
- Isotype: IgG
Product nameAnti-SR1 antibody
See all SR1 primary antibodies
DescriptionRabbit polyclonal to SR1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Horse, Cow, Dog, Human, Chimpanzee, Monkey
Predicted to work with: Chicken
Synthetic peptide (Human) sequence is amino acids 50-100 in length from Sorcin. (NP_003121).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab71983 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).|
|IHC-P||Use at an assay dependent concentration.|
FunctionCalcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Tissue specificityDetected in cardiac myocytes.
Sequence similaritiesContains 4 EF-hand domains.
Cellular localizationCytoplasm. Sarcoplasmic reticulum membrane. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
- Information by UniProt
- 22 kDa protein antibody
- Calcium binding protein amplified in mutlidrug resistant cells antibody
- CP 22 antibody
Paraffin embedded human small intestine tissue immunostained using ab71983 at 10 µg/ml.
All lanes : Anti-SR1 antibody (ab71983) at 1 µg/ml
Lane 1 : human brain lysate
Lane 2 : human brain lysate with immunising peptide
Lane 3 : mouse brain lysate
Lane 4 : rat brain lysate
Predicted band size: 22 kDa
Observed band size: 22 kDa
ab71983 has been referenced in 2 publications.
- Ranum PT et al. Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing. Cell Rep 26:3160-3171.e3 (2019). PubMed: 30865901
- Wright MF et al. Mechanisms of intracellular calcium homeostasis in developing and mature bovine corpora lutea. Biol Reprod 90:55 (2014). WB, ICC/IF ; Cow . PubMed: 24501170