Overview

  • Product name

    SR144528, peripheral CB2 receptor inverse agonist
  • Description

    Potent, selective peripheral CB2 receptor inverse agonist
  • Biological description

    Potent, selective peripheral CB2 receptor inverse agonist (Ki values are 0.6 and 400 nM for CB2 and CB1 receptors respectively). Decreases µ-opioid receptor expression. Enhances gastric motility in vivo.
  • Purity

    > 98%
  • CAS Number

    192703-06-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Krylatov AV  et al. Cannabinoid receptor antagonists SR141716 and SR144528 exhibit properties of partial agonists in experiments on isolated perfused rat heart. Bull Exp Biol Med 139:558-61 (2005). Read more (PubMed: 16224548) »
  • Rhee MH & Kim SK SR144528 as inverse agonist of CB2 cannabinoid receptor. J Vet Sci 3:179-84 (2002). Read more (PubMed: 12514329) »
  • Griffin G  et al. Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system. Eur J Pharmacol 377:117-25 (1999). Read more (PubMed: 10448934) »
See all 2 Publications for this product

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