Overview

  • Product name

  • Description

    Rabbit polyclonal to SR3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human SR3 aa 1-280.
    Database link: Q9HBF4

  • Positive control

    • WB: HeLa and HEK-293T whole cell lysates; Mouse liver and kidney lysates. IHC-P: Human pancreatic tissue.
  • General notes

    Previously labelled as ZFYVE1. 

Properties

Applications

Our Abpromise guarantee covers the use of ab224672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 87 kDa.
IHC-P 1/20 - 1/200.

Target

  • Relevance

    SR3 contains two zinc-binding FYVE domains in tandem. The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signalling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. There are two named isoforms of SR3.
  • Cellular localization

    Golgi apparatus, Golgi stack. Note: Resides predominantly in the cisternal stacks of the Golgi.
  • Database links

  • Alternative names

    • DFCP1 antibody
    • Double FYVE containing protein 1 antibody
    • KIAA1589 antibody
    • Phosphoinositide binding protein SR3 antibody
    • SR3 antibody
    • TAFF1 antibody
    • Tandem FYVE fingers 1 antibody
    • ZFYVE 1 antibody
    • ZFYVE1 antibody
    • Zinc finger FYVE domain containing protein 1 antibody
    • Zinc finger protein subfamily 2A (FYVE domain containing) 1 antibody
    • Zinc finger protein subfamily 2A member 1 antibody
    • ZNFN2A1 antibody
    see all

Images

  • All lanes : Anti-SR3 antibody (ab224672) at 1/1000 dilution

    Lane 1 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
    Lane 3 : Mouse liver lysate
    Lane 4 : Mouse kidney lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/10000 dilution

    Predicted band size: 87 kDa

  • Paraffin-embedded human pancreatic tissue stained for SR3 using ab224672 at 1/100 dilution in immunohistochemical analysis.

References

ab224672 has not yet been referenced specifically in any publications.

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