Overview

  • Product name
  • Description
    Goat polyclonal to SRCAP
  • Host species
    Goat
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Cow, Pig, Chimpanzee, Ferret, Monkey, Zebrafish, Gorilla, Bat, Elephant
  • Immunogen

    Synthetic peptide corresponding to Human SRCAP aa 309-322 (internal sequence) (Cysteine residue).
    Sequence:

    cQEGNDAEAQRREIE


    Database link: Q6ZRS2

  • Positive control
    • IHC-P: Human skin tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab219181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance
    Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription (from SwissProt).
  • Cellular localization
    Nuclear
  • Database links
  • Alternative names
    • domino homolog 2 antibody
    • DOMO1 antibody
    • EAF1 antibody
    • FLHS antibody
    • Helicase SRCAP antibody
    • KIAA0309 antibody
    • Snf2 related CBP activator protein antibody
    • Swi2/Snf2-related ATPase homolog, domino homolog 1 antibody
    • SWR1 antibody
    • SWR1, S. cerevisiae, homologof antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded formalin fixed human skin tissue labeling SRCAP using ab219181 at 5 µg/mL.

References

ab219181 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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