Key features and details
- Goat polyclonal to SREC-I
- Suitable for: ELISA, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-SREC-I antibody
See all SREC-I primary antibodies
DescriptionGoat polyclonal to SREC-I
SpecificityThis antibody is expected to recognise all 5 isoforms of SREC-I.
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Human
- Human heart lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab23933 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 85-90 kDa (predicted molecular weight: 87 kDa).
1 hour primary incubation is recommended for this product.
FunctionMediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
Tissue specificityEndothelial cells.
Sequence similaritiesContains 6 EGF-like domains.
- Information by UniProt
- Acetyl LDL receptor antibody
- Endothelial cells scavenger receptor antibody
- SCARF1 antibody
All lanes : Anti-SREC-I antibody (ab23933) at 0.3 µg/ml
Lane 1 : (A) Human Heart lysate
Lane 2 : (B) Human Heart lysate with immunizing peptide
Lysates/proteins at 35 µg per lane.
Predicted band size: 87 kDa
Observed band size: 85-90 kDa why is the actual band size different from the predicted?
Additional bands at: 28 kDa (possible non-specific binding)
Primary incubation was 1 hour. Detected by chemiluminescence.
ab23933 has been referenced in 1 publication.
- Narazaki M et al. Oligo-guanosinenucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood : (2010). ICC/IF ; Human . PubMed: 20606164