Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP2506(2)] to srGAP2
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Product nameAnti-srGAP2 antibody [EP2506(2)]
See all srGAP2 primary antibodies
DescriptionRabbit monoclonal [EP2506(2)] to srGAP2
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC,IHC-P or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide within Human srGAP2 aa 1000-1100. The exact sequence is proprietary.
- Mouse brain, SH SY5Y, 293T and JAR lysates.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant
Concentration information loading...
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab124958 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 140 kDa (predicted molecular weight: 121 kDa).|
FunctionPutative GTPase-activating protein for Rho family small GTPases.
Tissue specificityExpression at low levels in placenta, kidney, and ovary, and little or no expression in all other tissues tested.
Sequence similaritiesContains 1 FCH domain.
Contains 1 Rho-GAP domain.
Contains 1 SH3 domain.
- Information by UniProt
- ARHGAP34 antibody
- FBP2 antibody
- FNBP2 antibody
All lanes : Anti-srGAP2 antibody [EP2506(2)] (ab124958) at 1/1000 dilution
Lane 1 : Mouse brain lysates
Lane 2 : SH SY5Y lysates
Lane 3 : 293T lysates
Lane 4 : JAR lysates
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution
Predicted band size: 121 kDa
Observed band size: 140 kDa why is the actual band size different from the predicted?
ab124958 has been referenced in 1 publication.
- Sporny M et al. Structural History of Human SRGAP2 Proteins. Mol Biol Evol 34:1463-1478 (2017). PubMed: 28333212