Anti-SRP72 antibody - C-terminal (ab195308)
Key features and details
- Rabbit polyclonal to SRP72 - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-SRP72 antibody - C-terminal
See all SRP72 primary antibodies -
Description
Rabbit polyclonal to SRP72 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Sheep, Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Common marmoset, Orangutan, Elephant -
Immunogen
Synthetic peptide within Human SRP72 aa 600 to the C-terminus (C terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: O76094 -
Positive control
- HeLa, 293T and mouse NIH3T3 cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab195308 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2000 - 1/10000. Predicted molecular weight: 75 kDa.
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Notes |
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WB
1/2000 - 1/10000. Predicted molecular weight: 75 kDa. |
Target
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Function
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. -
Involvement in disease
Bone marrow failure, familial -
Sequence similarities
Belongs to the SRP72 family.
Contains 5 TPR repeats. -
Domain
The C-terminus is essential for the interaction with the SRP68/7S RNA complex. -
Cellular localization
Cytoplasm. Endoplasmic reticulum. - Information by UniProt
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Database links
- Entrez Gene: 403944 Dog
- Entrez Gene: 6731 Human
- Entrez Gene: 66661 Mouse
- Omim: 602122 Human
- SwissProt: P33731 Dog
- SwissProt: O76094 Human
- Unigene: 237825 Human
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Alternative names
- BMFF antibody
- BMFS1 antibody
- Epididymis luminal protein 103 antibody
see all
Images
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All lanes : Anti-SRP72 antibody - C-terminal (ab195308) at 0.1 µg/ml
Lane 1 : HeLa cell lysate
Lane 2 : 293T cell lysate
Lane 3 : Jurkat cell lysate
Lane 4 : Mouse TCMK-1 cell lysate
Lane 5 : Mouse NIH3T3 cell lysate
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 75 kDa
Exposure time: 30 seconds
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab195308 has not yet been referenced specifically in any publications.