Overview

  • Product name

    Anti-SRP72 antibody - C-terminal
    See all SRP72 primary antibodies
  • Description

    Rabbit polyclonal to SRP72 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Sheep, Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Common marmoset, Orangutan, Elephant
  • Immunogen

    Synthetic peptide within Human SRP72 aa 621-671 (C terminal). The exact sequence is proprietary.
    Sequence:

    SSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKG GW


    Database link: O76094

  • Positive control

    • HeLa, 293T and mouse NIH3T3 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab195308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 75 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function

      Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
    • Involvement in disease

      Bone marrow failure, familial
    • Sequence similarities

      Belongs to the SRP72 family.
      Contains 5 TPR repeats.
    • Domain

      The C-terminus is essential for the interaction with the SRP68/7S RNA complex.
    • Cellular localization

      Cytoplasm. Endoplasmic reticulum.
    • Information by UniProt
    • Database links

    • Alternative names

      • BMFF antibody
      • BMFS1 antibody
      • Epididymis luminal protein 103 antibody
      • HEL103 antibody
      • Signal recognition particle 72 kDa protein antibody
      • Signal recognition particle 72kDa antibody
      • Signal recognition particle subunit SRP72 antibody
      • SRP72 antibody
      • SRP72_HUMAN antibody
      see all

    Images

    • All lanes : Anti-SRP72 antibody - C-terminal (ab195308) at 0.1 µg/ml

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : Mouse TCMK-1 cell lysate
      Lane 5 : Mouse NIH3T3 cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 75 kDa


      Exposure time: 30 seconds

    References

    ab195308 has not yet been referenced specifically in any publications.

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