Anti-SRPRB antibody (ab16146)
Key features and details
- Sheep polyclonal to SRPRB
- Suitable for: WB
- Reacts with: Dog
- Isotype: IgG
Overview
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Product name
Anti-SRPRB antibody
See all SRPRB primary antibodies -
Description
Sheep polyclonal to SRPRB -
Host species
Sheep -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Dog -
Immunogen
Synthetic peptide corresponding to Dog SRPRB aa 246-265 (C terminal).
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Positive control
- Canine microsomal protein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Ammonium Sulphate Precipitation -
Purification notes
Purified by ammonium sulfate precipitation This antibody is provided as a 0.2 µm sterile filtered solution. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab16146 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa.
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Notes |
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WB
Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa. |
Target
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Function
Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR. -
Sequence similarities
Belongs to the SRP receptor beta subunit family. -
Cellular localization
Endoplasmic reticulum membrane. - Information by UniProt
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Alternative names
- APMCF1 antibody
- Protein APMCF1 antibody
- Signal recognition particle receptor B subunit antibody
see all
Images
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ab16146 detecting SRPRB from canine microsomal protein by western blot
Lane 1: 3ng of canine microsomal protein
Lane 2: 6ng of canine microsomal protein
Lane 3: 12ng of canine microsoaml protein
ab16146 detecting SRPRB from canine microsomal protein by western blot Lane 1: 3ng of canine microsomal protein Lane 2: 6ng of canine microsomal protein Lane 3: 12ng of canine microsoaml protein
Datasheets and documents
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Datasheet download
References (1)
ab16146 has been referenced in 1 publication.
- Lakkaraju AK et al. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell 23:2712-22 (2012). WB . PubMed: 22648169