Key features and details
- Rabbit polyclonal to SRPRB
- Suitable for: IHC-P, WB
- Reacts with: Human, Pig
- Isotype: IgG
Product nameAnti-SRPRB antibody
See all SRPRB primary antibodies
DescriptionRabbit polyclonal to SRPRB
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human, Pig
Predicted to work with: Mouse, Rat
Recombinant fragment (His-T7-tag) corresponding to Human SRPRB aa 58-271. Expressed in E.coli. N-terminal tags.
RSR RSSQRAVLLV GLCDSGKTLL FVRLLTGLYR DTQTSITDSC AVYRVNNNRG NSLTLIDLPG HESLRLQFLE RFKSSARAIV FVVDSAAFQR EVKDVAEFLY QVLIDSMGLK NTPSFLIACN KQDIAMAKSA KLIQQQLEKE LNTLRVTRSAAPSTLDSSST APAQLGKKGK EFEFSQLPLK VEFLECSAKG GRGDVGSADI QDLEKWLAKIA
Database link: Q9Y5M8
- WB: Porcine cerebrum, liver and pancreas lysate; HepG2 cell lysate. Recombinant human SRPRB protein. IHC-P: Human pancreas tissue.
This product was previously labelled as SRPR beta
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesFollowed by Protein A affinity chromatography.
Our Abpromise guarantee covers the use of ab231276 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 20 µg/ml.|
|WB||Use a concentration of 0.2 - 2 µg/ml.|
FunctionComponent of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
Sequence similaritiesBelongs to the SRP receptor beta subunit family.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
- APMCF1 antibody
- Protein APMCF1 antibody
- Signal recognition particle receptor B subunit antibody
Formalin-fixed, paraffin-embedded human pancreas tissue stained for SRPRB with ab231276 at 20 µg/ml in immunohistochemical analysis. DAB staining.
Anti-SRPRB antibody (ab231276) at 2 µg/ml + HepG2 (human liver hepatocellular carcinoma cell line) lysate
Anti-SRPRB antibody (ab231276) at 2 µg/ml + Porcine pancreas lysate
Anti-SRPRB antibody (ab231276) at 2 µg/ml + Porcine liver lysate
Anti-SRPRB antibody (ab231276) at 2 µg/ml + Porcine cerebrum lysate
Anti-SRPRB antibody (ab231276) at 2 µg/ml + Recombinant human SRPRB protein
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab231276 has not yet been referenced specifically in any publications.