Overview

  • Product name

    Anti-SSH2 antibody
  • Description

    Rabbit polyclonal to SSH2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human SSH2 aa 1-178.
    Sequence:

    MIPYFSANAVISQNAINQLISESFLTVKGAALFLPRGNGSSTPRISHRRN KHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQD TEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVH IFKPVSVQAMWVDRDSRNKHCDVLLVEE


    Database link: AAH11636.2

  • Positive control

    • SSH2 transfected 293T cell lysate, recombinant SSH2 protein

Properties

Applications

Our Abpromise guarantee covers the use of ab118079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 158 kDa.

Different isoforms of SSH2 may produce bands at a lower molecular weight to the predicted.

Target

  • Function

    Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • hSSH 2L antibody
    • hSSH-2L antibody
    • KIAA1725 antibody
    • MGC78588 antibody
    • OTTHUMP00000163634 antibody
    • OTTHUMP00000163635 antibody
    • Protein phosphatase Slingshot homolog 2 antibody
    • Slingshot 2 antibody
    • Slingshot homolog 2 (Drosophila) antibody
    • Slingshot homolog 2 antibody
    • Slingshot2 antibody
    • SSH 2 antibody
    • SSH 2L antibody
    • SSH-2L antibody
    • SSH-like protein 2 antibody
    • SSH2 antibody
    • SSH2_HUMAN antibody
    • SSH2L antibody
    see all

Images

  • All lanes : Anti-SSH2 antibody (ab118079)

    Lane 1 : SSH2 transfected 293T cell lysate(19.90 KDa)
    Lane 2 : Non-transfected 293T cell lysate.

    Predicted band size: 158 kDa
    Observed band size: 20 kDa
    why is the actual band size different from the predicted?

References

ab118079 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab118079.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up