Overview

  • Product name

  • Description

    Rabbit polyclonal to SSX2IP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Cow, Human, Chimpanzee, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human SSX2IP (internal sequence). The exact sequence is proprietary.
    Database link: Q9Y2D8

  • Positive control

    • WB: Neuro-2a, GL261 and C8D30 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab227517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 71 kDa.

Target

  • Function

    Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin.
  • Tissue specificity

    Widely expressed, with the highest expression in brain, intermediate expression in kidney, testis, spinal cord, liver, heart, lung, skeletal muscle, ovary, fetal liver and fetal brain, and little to no expression in pancreas and spleen. All specific brain regions showed intermediate to high expression, with highest expression in amygdala. Also expressed in fetal tissues, mainly in liver and brain.
  • Domain

    Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.
  • Cellular localization

    Cell junction > adherens junction. Nucleus. Not found at cell-matrix AJs.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADIP antibody
    • ADIP_HUMAN antibody
    • Afadin and alpha actinin binding protein antibody
    • Afadin DIL domain interacting protein antibody
    • Afadin DIL domain-interacting protein antibody
    • Afadin- and alpha-actinin-binding protein antibody
    • FLJ10848 antibody
    • KIAA0923 antibody
    • MGC75026 antibody
    • OTTHUMP00000011574 antibody
    • SSX 2 interacting protein antibody
    • SSX2 interacting protein antibody
    • SSX2-interacting protein antibody
    • SSX2IP antibody
    • Synovial sarcoma X breakpoint 2 interacting protein antibody
    see all

Images

  • All lanes : Anti-SSX2IP antibody (ab227517) at 1/1000 dilution

    Lane 1 : Neuro-2a (mouse neuroblastoma cell line) whole cell lysate
    Lane 2 : GL261 whole cell lysate
    Lane 3 : C8D30 (mouse astrocyte cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 71 kDa



    7.5% SDS-PAGE

References

ab227517 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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