Key features and details
- Mouse monoclonal [6B72] to ST2
- Suitable for: WB, Neutralising
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-ST2 antibody [6B72]
See all ST2 primary antibodies
DescriptionMouse monoclonal [6B72] to ST2
Tested applicationsSuitable for: WB, Neutralisingmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human ST2 aa 19-327 (extracellular). (NP_057316.3 ).
KFSKQSWGLENEALIVRCPRQGKPSYTVDWYYSQTNKSIPTQERNRVFAS GQLLKFLPAAVADSGIYTCIVRSPTFNRTGYANVTIYKKQSDCNVPDYLM YSTVSGSEKNSKIYCPTIDLYNWTAPLEWFKNCQALQGSRYRAHKSFLVI DNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPA QNEIKEVEIGKNANLTCSACFGKGTQFLAAVLWQLNGTKITDFGEPRIQQ EEGQNQSFSNGLACLDMVLRIADVKEEDLLLQYDCLALNLHGLRRHTVRL SRKNPIDHH
Database link: Q01638
FormLyophilized:Reconstitute the antibody with 200 µl sterile PBS and the final concentration is 500 µg/ml. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituent: 100% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab196525 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 63 kDa.|
|Neutralising||Use at an assay dependent concentration.|
FunctionReceptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
Tissue specificityHighly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
Sequence similaritiesBelongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- DER-4 antibody
- DER4 antibody
- FIT 1 antibody
ab196525 has been referenced in 1 publication.
- Al-Sajee D et al. Expression of IL-33 and TSLP and Their Receptors in Asthmatic Airways after Inhaled Allergen Challenge. Am J Respir Crit Care Med 198:805-807 (2018). PubMed: 29733677