Anti-ST3GAL2 antibody (ab96028)
Key features and details
- Rabbit polyclonal to ST3GAL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ST3GAL2 antibody
See all ST3GAL2 primary antibodies -
Description
Rabbit polyclonal to ST3GAL2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 68 and 297 of Human ST3GAL2 (UniProt ID: Q16842).
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Positive control
- 293T, A431, HeLaS3, HepG2, MOLT4, Raji and H1299 whole cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96028 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
Target
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Function
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. -
Tissue specificity
Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. -
Pathway
Protein modification; protein glycosylation. -
Sequence similarities
Belongs to the glycosyltransferase 29 family. -
Post-translational
modificationsThe soluble form derives from the membrane form by proteolytic processing. -
Cellular localization
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. - Information by UniProt
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Database links
- Entrez Gene: 6483 Human
- Entrez Gene: 20444 Mouse
- Entrez Gene: 64442 Rat
- Omim: 607188 Human
- SwissProt: Q16842 Human
- SwissProt: Q11204 Mouse
- SwissProt: Q11205 Rat
- Unigene: 368611 Human
see all -
Alternative names
- 3-GalNAc-alpha-2 antibody
- 3-sialyltransferase 2 antibody
- 3-sialyltransferase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab96028 has been referenced in 2 publications.
- Li Y et al. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. Lab Invest 96:731-40 (2016). PubMed: 27088512
- Ali MF et al. Golgi Phosphoprotein 3 Determines Cell Binding Properties under Dynamic Flow by Controlling Golgi Localization of Core 2 N-Acetylglucosaminyltransferase 1. J Biol Chem 287:39564-77 (2012). ICC/IF . PubMed: 23027862