Anti-ST3GAL2 antibody (ab96028)
Key features and details
- Rabbit polyclonal to ST3GAL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ST3GAL2 antibody
See all ST3GAL2 primary antibodies -
Description
Rabbit polyclonal to ST3GAL2 -
Host species
Rabbit -
Tested Applications & Species
Application Species WB Human -
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 68 and 297 of Human ST3GAL2 (UniProt ID: Q16842).
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Positive control
- 293T, A431, HeLaS3, HepG2, MOLT4, Raji and H1299 whole cell lysates
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96028 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
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WB |
Human
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All applications |
Mouse
Rat
Cow
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Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
Target
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Function
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. -
Tissue specificity
Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. -
Pathway
Protein modification; protein glycosylation. -
Sequence similarities
Belongs to the glycosyltransferase 29 family. -
Post-translational
modificationsThe soluble form derives from the membrane form by proteolytic processing. -
Cellular localization
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. - Information by UniProt
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Database links
- Entrez Gene: 6483 Human
- Entrez Gene: 20444 Mouse
- Entrez Gene: 64442 Rat
- Omim: 607188 Human
- SwissProt: Q16842 Human
- SwissProt: Q11204 Mouse
- SwissProt: Q11205 Rat
- Unigene: 368611 Human
see all -
Alternative names
- 3-GalNAc-alpha-2 antibody
- 3-sialyltransferase 2 antibody
- 3-sialyltransferase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab96028 has been referenced in 2 publications.
- Li Y et al. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. Lab Invest 96:731-40 (2016). PubMed: 27088512
- Ali MF et al. Golgi Phosphoprotein 3 Determines Cell Binding Properties under Dynamic Flow by Controlling Golgi Localization of Core 2 N-Acetylglucosaminyltransferase 1. J Biol Chem 287:39564-77 (2012). ICC/IF . PubMed: 23027862