Overview

  • Product name

  • Description

    Rabbit polyclonal to ST5
  • Host species

    Rabbit
  • Specificity

    No cross reactivity with other proteins.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ST5 aa 571-586 (internal sequence).
    Sequence:

    KRHSHDDMLLLAQLSL


    Database link: P78524

Properties

Applications

Our Abpromise guarantee covers the use of ab187759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 126 kDa.

Target

  • Function

    May be involved in cytoskeletal organization and tumorgenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
  • Tissue specificity

    Widely expressed with the exception of peripheral blood lymphocytes. Isoform 1 is expressed in several epithelial and fibroblast (including tumorigenic) but absent in lymphoid cell lines (at protein level). Isoform 3 is expressed in primary cell or weakly tumorigenic but not in tumorigenic cell lines (at protein level).
  • Sequence similarities

    Contains 1 dDENN domain.
    Contains 1 DENN domain.
    Contains 1 uDENN domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • DENND2B antibody
    • DENN domain containing protein 2B antibody
    • DENN domain-containing protein 2B antibody
    • DENN/MADD domain containing 2B antibody
    • HeLa tumor suppression 1 antibody
    • HTS1 antibody
    • p126 antibody
    • ST 5 antibody
    • ST5 antibody
    • ST5_HUMAN antibody
    • Suppression of tumorigenicity 5 antibody
    • Suppression of tumorigenicity 5 protein antibody
    see all

Images

  • All lanes : Anti-ST5 antibody (ab187759) at 0.5 µg/ml

    Lane 1 : Rat Testis Tissue Lysate
    Lane 2 : A431 Whole Cell Lysate
    Lane 3 : HeLa Whole Cell Lysate
    Lane 4 : COLO320 Whole Cell Lysate
    Lane 5 : NIH Whole Cell Lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 126 kDa

References

ab187759 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab187759.
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