Recombinant Anti-Stanniocalcin 1/STC antibody [EPR6055] (ab124891)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR6055] to Stanniocalcin 1/STC
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
Overview
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Product name
Anti-Stanniocalcin 1/STC antibody [EPR6055]
See all Stanniocalcin 1/STC primary antibodies -
Description
Rabbit monoclonal [EPR6055] to Stanniocalcin 1/STC -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: ICC/IF or IHC-P -
Species reactivity
Reacts with: Human
Does not react with: Mouse, Rat -
Immunogen
Synthetic peptide within Human Stanniocalcin 1/STC aa 200-300 (C terminal). The exact sequence is proprietary.
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Positive control
- Human Prostate, Ovary cancer and Plasma lysates.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Dissociation constant (KD)
KD = 2.10 x 10 -12 M Learn more about KD -
Storage buffer
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR6055 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab124891 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Detects a band of approximately 31-35 kDa (predicted molecular weight: 28 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 31-35 kDa (predicted molecular weight: 28 kDa). |
Target
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Function
Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. -
Tissue specificity
Expressed in most tissues, with the highest levels in ovary, prostate, heart, kidney and thyroid. In the kidney, expression is confined to the nephron, specifically in the distal convoluted tubule and in the collecting tubule. Not detected in the brain, liver, spleen, peripheral blood leukocytes and adrenal medulla. -
Sequence similarities
Belongs to the stanniocalcin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6781 Human
- Omim: 601185 Human
- SwissProt: P52823 Human
- Unigene: 25590 Human
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Alternative names
- Stanniocalcin 1 antibody
- Stanniocalcin antibody
- Stanniocalcin-1 antibody
see all
Images
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All lanes : Anti-Stanniocalcin 1/STC antibody [EPR6055] (ab124891) at 1/1000 dilution
Lane 1 : Human Prostate lysate
Lane 2 : Human Ovary cancer lysate
Lane 3 : Human Plasma lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-Rabbit HRP at 1/2000 dilution
Predicted band size: 28 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab124891 has been referenced in 2 publications.
- Zhang C et al. Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1. Front Cell Dev Biol 9:622344 (2021). PubMed: 33644060
- Mou Z et al. Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma. Front Genet 11:566918 (2020). PubMed: 33424916