Overview

  • Product name

    Anti-STAT4 (phospho Y693) antibody
    See all STAT4 primary antibodies
  • Description

    Rabbit polyclonal to STAT4 (phospho Y693)
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human STAT4 (phospho Y693). The exact sequence is proprietary. A phospho specific peptide corresponding to residues surrounding Y693 of Human STAT4.
    Database link: Q14765

  • Positive control

    • IL4-treated HepG2 cell extract; Human breast carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab194732 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 86 kDa.
IHC-P 1/50 - 1/100.

Target

  • Function

    Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
  • Involvement in disease

    Systemic lupus erythematosus 11
    Rheumatoid arthritis
  • Sequence similarities

    Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • Post-translational
    modifications

    Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
  • Cellular localization

    Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • Database links

  • Alternative names

    • Signal transducer and activator of transcription 4 antibody
    • SLEB11 antibody
    • STAT4 antibody
    • STAT4_HUMAN antibody

Images

  • All lanes : Anti-STAT4 (phospho Y693) antibody (ab194732) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HepG2 cell extract treated with IL4

    Predicted band size: 86 kDa

  • Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue labeling STAT4 (phospho Y693) with ab194732 at 1/50 dilution.

References

ab194732 has not yet been referenced specifically in any publications.

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