Name: Anti-STAT5a (phospho S726) antibody [EPR1914(2)]
Brand: RabMAb
SKU: ab128896

Product name

Anti-STAT5a (phospho S726) antibody [EPR1914(2)]
See all STAT5a primary antibodies
Description

Rabbit monoclonal [EPR1914(2)] to STAT5a (phospho S726)
Host species

Rabbit
Specificity

ab128896 only detects STAT5a phosphorylated at Serine 726
Tested applications

Suitable for: Dot blot, WBmore details
Unsuitable for: FuncS,ICC or IHC-P
Species reactivity

Reacts with: Mouse, Rat, Human
Immunogen

Phospho specific peptide corresponding to residues surrounding Ser726 of Human STAT5a (UniProt P42229).
Positive control
- SH-SY5Y cell lysates treated with Okadaic acid and Calyculin A.
General notes

A trial size is available to purchase for this antibody.

Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab^® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
This product is a recombinant rabbit monoclonal antibody.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer

pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.5% BSA
Concentration information loading...
Purity

Protein A purified
Clonality

Monoclonal
Clone number

EPR1914(2)
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab128896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
Dot blot		1/1000.
WB		1/1000 - 1/10000. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).

Application notes

Is unsuitable for FuncS,ICC or IHC-P.

Function

Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
Sequence similarities

Belongs to the transcription factor STAT family.
Contains 1 SH2 domain.
Post-translational
modifications

Tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity.
Cellular localization

Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
Target information above from: UniProt accession P42229 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 6776 Human
- Entrez Gene: 20850 Mouse
- Entrez Gene: 24918 Rat
- Omim: 601511 Human
- SwissProt: P42229 Human
- SwissProt: P42230 Mouse
- SwissProt: Q62771 Rat
- Unigene: 437058 Human
- Unigene: 277403 Mouse
- Unigene: 154399 Rat
see all
Alternative names
- Mammary gland factor antibody
- MGF antibody
- Signal transducer and activator of transcription 5A antibody
- STA5A_HUMAN antibody
- STAT 5 antibody
- STAT 5A antibody
- STAT5 antibody
- STAT5A antibody
see all

ab128896 has not yet been referenced specifically in any publications.

Publishing research using ab128896? Please let us know so that we can cite the reference in this datasheet.

Recombinant Anti-STAT5a (phospho S726) antibody [EPR1914(2)] (ab128896)

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