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Rabbit polyclonal to Staufen
At least three isoforms of Staufen are known to exist; ab105398 will detect all three.
Mouse, Rat, Human
A 15 amino acid synthetic peptide from near the carboxy terminus of Human Staufen (NP_059347).(Peptide available as
Shipped at 4°C. Store at +4°C.
Preservative: 0.02% Sodium Azide
Concentration information loading...
Immunogen affinity purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 63 kDa.Can be blocked with
Staufen peptide (ab110446).
Use a concentration of 10 µg/ml.
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
Contains 3 DRBM (double-stranded RNA-binding) domains.
One of the DRDB could be involved in RER binding.
The C-terminal contains the tubulin binding domain (TBD).
Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
Information by UniProt
Double stranded RNA binding protein Staufen homolog 1 antibody
Double stranded RNA binding protein Staufen homolog antibody
Double-stranded RNA-binding protein Staufen homolog 1 antibody
Western blot - Anti-Staufen antibody (ab105398)
Lane 1 : Anti-Staufen antibody (ab105398) at 1 µg/ml Lane 2 : Anti-Staufen antibody (ab105398) at 2 µg/ml All lanes : Rat brain tissue lysate Lysates/proteins at 15 µg per lane. Predicted band size: 63 kDa
Immunocytochemistry - Anti-Staufen antibody (ab105398)
Immunohistochemistry of Staufen in Human brain tissue with ab105398 at 10 µg/ml.
Immunocytochemistry/ Immunofluorescence - Anti-Staufen antibody (ab105398)
Immunofluorescence of STAU1 in Human Brain cells using ab105398 at 20 ug/ml.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"