• Product name

    Anti-Staufen/STAU1 antibody
    See all Staufen/STAU1 primary antibodies
  • Description

    Rabbit polyclonal to Staufen/STAU1
  • Host species

  • Specificity

    At least three isoforms of Staufen/STAU1 are known to exist; ab105398 will detect all three.

  • Tested applications

    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Staufen/STAU1 (C terminal).
    Database link: NP_059347
    (Peptide available as ab110446)

  • Positive control

    • Rat brain tissue lysate.
  • General notes

     This product was previously labelled as Staufen




Our Abpromise guarantee covers the use of ab105398 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 63 kDa.
ICC Use a concentration of 10 µg/ml.


  • Function

    Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
  • Tissue specificity

    Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
  • Sequence similarities

    Contains 3 DRBM (double-stranded RNA-binding) domains.
  • Domain

    One of the DRDB could be involved in RER binding.
    The C-terminal contains the tubulin binding domain (TBD).
  • Cellular localization

    Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
  • Information by UniProt
  • Database links

  • Alternative names

    • Double stranded RNA binding protein Staufen homolog 1 antibody
    • Double stranded RNA binding protein Staufen homolog antibody
    • Double-stranded RNA-binding protein Staufen homolog 1 antibody
    • FLJ25010 antibody
    • MGC124588 antibody
    • PPP1R150 antibody
    • STAU antibody
    • STAU1 antibody
    • STAU1_HUMAN antibody
    • staufen antibody
    • Staufen RNA binding protein (Drosophila) antibody
    • Staufen RNA binding protein homolog 1 antibody
    • Staufen, Drosophila, homolog of, 1 antibody
    • Staufen, RNA binding protein, homolog 1 (Drosophila) antibody
    • staufen-like antibody
    see all


  • Lane 1 : Anti-Staufen/STAU1 antibody (ab105398) at 1 µg/ml
    Lane 2 : Anti-Staufen/STAU1 antibody (ab105398) at 2 µg/ml

    All lanes : Rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 63 kDa

  • Immunohistochemistry of Staufen/STAU1 in Human brain tissue with ab105398 at 10 µg/ml.

  • Immunofluorescence of STAU1 in Human Brain cells using ab105398 at 20 ug/ml.


This product has been referenced in:

  • Ricci EP  et al. Staufen1 senses overall transcript secondary structure to regulate translation. Nat Struct Mol Biol 21:26-35 (2014). Read more (PubMed: 24336223) »
See 1 Publication for this product

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