Overview

  • Product name

    Anti-Staufen/STAU1 antibody
    See all Staufen/STAU1 primary antibodies
  • Description

    Rabbit polyclonal to Staufen/STAU1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Recombinant fragment within Human Staufen/STAU1 (internal sequence). The exact sequence is proprietary.
    Database link: O95793

  • Positive control

    • WB: Raji whole cell lysate. IHC-P: Human colon carcinoma tissue. ICC/IF: A431 cells.
  • General notes

     This product was previously labelled as Staufen

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 63 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
  • Tissue specificity

    Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
  • Sequence similarities

    Contains 3 DRBM (double-stranded RNA-binding) domains.
  • Domain

    One of the DRDB could be involved in RER binding.
    The C-terminal contains the tubulin binding domain (TBD).
  • Cellular localization

    Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
  • Information by UniProt
  • Database links

  • Alternative names

    • Double stranded RNA binding protein Staufen homolog 1 antibody
    • Double stranded RNA binding protein Staufen homolog antibody
    • Double-stranded RNA-binding protein Staufen homolog 1 antibody
    • FLJ25010 antibody
    • MGC124588 antibody
    • PPP1R150 antibody
    • STAU antibody
    • STAU1 antibody
    • STAU1_HUMAN antibody
    • staufen antibody
    • Staufen RNA binding protein (Drosophila) antibody
    • Staufen RNA binding protein homolog 1 antibody
    • Staufen, Drosophila, homolog of, 1 antibody
    • Staufen, RNA binding protein, homolog 1 (Drosophila) antibody
    • staufen-like antibody
    see all

Images

  • Anti-Staufen/STAU1 antibody (ab228773) at 1/1000 dilution + Raji (human Burkitt's lymphoma cell line) whole cell lysate at 30 µg

    Predicted band size: 63 kDa



    7.5% SDS-PAGE gel.

  • Ice-cold methanol-fixed A431 (human epidermoid carcinoma cell line) cells stained for Staufen/STAU1 using ab228773 (green) at 1/500 dilution in ICC/IF.

    Nuclear counterstain: Hoechst 33342 (blue).

  • Paraffin-embedded human colon carcinoma tissue stained for Staufen/STAU1 using ab228773 at 1/500 dilution in immunohistochemical analysis.

  • 4% paraformaldehyde-fixed DIV9 rat E18 primary hippocampal neurons labeling Staufen/STAU1 using ab228773 at 1/500 dilution in ICC/IF.

    The nuclear counter stain is Fluoroshield with DAPI (blue). Beta Tubulin 3 /Tuj1 is labeled with a beta Tubulin / Tuj1 antibidy (red).

References

ab228773 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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