Overview

  • Product name

  • Description

    Rabbit polyclonal to STK17A
  • Host species

    Rabbit
  • Specificity

    No reactivity to DRAK2, DAP or ZIP kinases.
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human STK17A aa 5-19.
    Sequence:

    EKPGSGGSSPGATSGC


    (Peptide available as ab8453)

  • Positive control

    • A431 or MOLT4 whole cell lysate An approximately 50 kDa band can be detected.
  • General notes

     This product was previously labelled as DRAK1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab8418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 50 kDa.
ICC/IF Use a concentration of 2 µg/ml.

Target

  • Function

    Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
  • Tissue specificity

    Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Autophosphorylated.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DAP kinase-related apoptosis-inducing protein kinase 1 antibody
    • death-associated protein kinase-related 1 antibody
    • DRAK1 antibody
    • EC 2.7.11.1 antibody
    • Serine / threonine kinase 17a death associated protein kinase related 1 antibody
    • Serine/threonine kinase 17a antibody
    • Serine/threonine protein kinase 17a antibody
    • Serine/threonine-protein kinase 17A antibody
    • ST17A_HUMAN antibody
    • STK17 A antibody
    • STK17A antibody
    see all

Images

  • All lanes : Anti-STK17A antibody (ab8418) at 1/500 dilution

    Lane 1 : MOLT4 whole cell lysate
    Lane 2 : A431 whole cell lysate
    Lane 3 : 3T3 whole cell lysate

    Observed band size: 50 kDa
    why is the actual band size different from the predicted?

  • ab8418 at 2µg/ml staining STK17A in MOLT4 cells by ICC/IF

References

This product has been referenced in:

  • Zou Y  et al. LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells. Eur J Cell Biol 97:369-378 (2018). WB ; Human . Read more (PubMed: 29773344) »
See 1 Publication for this product

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There are currently no Customer reviews or Questions for ab8418.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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