STO-609 acetate, CaM-KK inhibitor (ab141591)
Key features and details
- Potent, competitive, selective and cell-permeable inhibitor of CaM-KK
- CAS Number: 1173022-21-3
- Purity: > 98%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
STO-609 acetate, CaM-KK inhibitor -
Description
Potent, competitive, selective and cell-permeable inhibitor of CaM-KK -
Biological description
Potent, competitive, selective and cell-permeable inhibitor of CaM-KK (Ki values are0.21 µM and 40 nM for CaM-KKα and CaM-KKβ respectively). Potent, competitive AhR agonist (EC50 = 43 nM). Active in vivo. -
Purity
> 98% -
CAS Number
1173022-21-3 -
Chemical structure
Properties
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Chemical name
7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate
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Molecular weight
374.35 -
Molecular formula
C19H10N2O3.C2H4O2 -
PubChem identifier
16760660 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM
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Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (3)
ab141591 has been referenced in 3 publications.
- Ferdowsi PV et al. Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium Signalling Pathway. Int J Mol Sci 23:N/A (2022). PubMed: 35216322
- Xie B et al. Induction of autophagy and suppression of type I IFN secretion by CSFV. Autophagy 17:925-947 (2021). PubMed: 32160078
- LeBlond ND et al. Foam Cell Induction Activates AMPK But Uncouples Its Regulation of Autophagy and Lysosomal Homeostasis. Int J Mol Sci 21:N/A (2020). PubMed: 33261140