Overview

  • Product name

    Anti-STOP antibody
  • Description

    Rabbit polyclonal to STOP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Frmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment within Human STOP (internal sequence). The exact sequence is proprietary.
    Database link: Q96JE9

  • Positive control

    • WB: Mouse and rat brain tissue extract. IHC-Fr: Adult mouse cerebellum tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab229503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/10000. Predicted molecular weight: 87 kDa.
IHC-Fr 1/100 - 1/1000.

Target

  • Function

    Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity.
  • Tissue specificity

    Expressed in brain (at protein level). Expressed in spinal chord. Isoform 2 expression is up-regulated in the prefrontal cortex (Brodmann's area 46) of patients with schizophrenia (postmortem brain study).
  • Sequence similarities

    Belongs to the STOP family.
  • Cellular localization

    Cytoplasm > cytoskeleton. Golgi apparatus. Colocalizes with neurofilament (NF)-rich inclusions in spinal chord and brain neurons of patients with amyotrophic lateral sclerosis.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ41346 antibody
    • KIAA1878 antibody
    • MAP 6 antibody
    • MAP-6 antibody
    • MAP6 antibody
    • MAP6_HUMAN antibody
    • Microtubule associated protein 6 antibody
    • Microtubule-associated protein 6 antibody
    • MTAP6 antibody
    • N STOP antibody
    • Stable tubule only polypeptide antibody
    • Stable tubule-only polypeptide antibody
    • STOP antibody
    see all

Images

  • Frozen sectioned adult mouse cerebellum stained for STOP with ab229503 (green) at a 1/250 dilution in immunohistochemical analysis. NF-H (red) and DAPI (blue).

  • Anti-STOP antibody (ab229503) at 1/1000 dilution + Mouse brain tissue extracts at 50 µg

    Developed using the ECL technique.

    Predicted band size: 87 kDa



    7.5% SDS-PAGE

  • Anti-STOP antibody (ab229503) at 1/5000 dilution + Rat brain tissue extracts at 50 µg

    Developed using the ECL technique.

    Predicted band size: 87 kDa



    7.5% SDS-PAGE

References

ab229503 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229503.
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