Key features and details
- Rabbit polyclonal to STOX1 - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-STOX1 antibody - C-terminal
See all STOX1 primary antibodies
DescriptionRabbit polyclonal to STOX1 - C-terminal
SpecificityAt least three alternatively spliced transcript variants encoding distinct isoforms have been observed. ab189436 will recognize the longest isoform.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human STOX1 (C terminal). Raised against a 14 amino acid peptide near the C-terminal end.
Database link: Q6ZVD7
- Human liver lysate. Human adrenal or skeletal muscle tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189436 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 111 kDa.|
Involvement in diseaseDefects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4) [MIM:609404]; also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta.
Cellular localizationNucleus; Nucleus > nucleolus and Cytoplasm. Nucleus. Either found in the cytoplasm or in the nucleus. Nuclear expression of isoform A seems to be restricted to polyploid trophoblast cells.
- Information by UniProt
- C10orf24 antibody
- chromosome 10 open reading frame 241 antibody
- PEE4 antibody
All lanes : Anti-STOX1 antibody - C-terminal (ab189436) at 1 µg/ml
Lane 1 : Human liver lysate
Lane 2 : Human liver lysate plus blocking peptide
Predicted band size: 111 kDa
Immunohistochemical analysis of formalin fixed, paraffin embedded human skeletal muscle labeling STOX1 with ab189436 at 5 μg/ml.
Immunohistochemical analysis of formalin fixed, paraffin embedded human adrenal tissue labeling STOX1 with ab189436 at 5 μg/ml.
ab189436 has not yet been referenced specifically in any publications.