Overview

  • Product name

    Streptochlorin, Antiangiogenic agent
  • Description

    Potent antiangiogenic agent
  • Biological description

    Potent antiangiogenic agent. Induces ROS-mediated apoptosis. Inhibits TNF-α-induced NF-κB activation. Shows selective cytotoxic effects against cancer cell lines. Inhibits mast cell degranulation. Shows potent anti-allergic effects in vivo.
  • Purity

    > 95%
  • CAS Number

    120191-51-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lee SH  et al. Streptochlorin suppresses allergic dermatitis and mast cell activation via regulation of Lyn/Fyn and Syk signaling pathways in cellular and mouse models. PLoS One 8:e74194 (2013). Read more (PubMed: 24086321) »
  • Shin DY  et al. Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway. J Microbiol Biotechnol 18:1862-8 (2008). Read more (PubMed: 19047834) »
  • Choi IK  et al. Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro. J Microbiol Biotechnol 17:1338-43 (2007). Read more (PubMed: 18051603) »

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